by Fabio Bergamin, ETH Zurich Scheme of the two-step procedure for accumulating and finally releasing encapsulated drugs locally. Researchers at ETH Zurich have developed a method for concentrating and releasing drugs in the brain with pinpoint accuracy. This could make it possible in the future to deliver psychiatric and cancer drugs and other medications only to those...
by Oklahoma Medical Research Foundation An Oklahoma Medical Research Foundation discovery could pave the way for therapies to reverse vision loss common in premature infants and adults. In a new study appearing in the Proceedings of the National Academy of Sciences, OMRF scientists have identified a compound that could give birth to therapies for a host of eye diseases that...
by Ludwig Institute for Cancer Research A Ludwig Cancer Research study has uncovered a mechanism by which the tumor’s harsh internal environment sabotages T lymphocytes, leading cellular agents of the anticancer immune response. Reported in Nature Immunology, the study describes how a variety of stressors prevalent in the tumor microenvironment disrupt the power generators, or mitochondria, of tumor-infiltrating T lymphocytes (TILs),...
by National Institutes of Health NIH scientists discovered that intense neural conversations thought to underlie learning and memory may be fueled by an energy-sensing feedback loop. Here scientist monitored energy levels in the form of ATP as neurons talked to each other. Our thoughts, feelings, and movements are controlled by billions of neurons talking to each...
CHILDREN’S HOSPITAL OF PHILADELPHIA Philadelphia, October 5, 2020–Through genetic sequencing and targeted treatment, researchers from Children’s Hospital of Philadelphia (CHOP) have resolved a severe lymphatic disorder in a young woman with kaposiform lymphangiomatosis (KLA), a complex and rare disorder that causes lymphatic vessels around the heart and lung to leak fluid, causing breathing difficulties, infections, and often...
by Max Planck Society A picture show with ultrasound: Stuttgart researchers are writing the alphabet using micro-particles by modulating sound pressure profiles. Depending on the sound pressure, the particles collect and form letters. With the letter images, the team demonstrates the possibilities of the ultrasound modulator, which will likely be used primarily in medicine. A chip-based...
by Zachary Sweger, Pennsylvania State University T cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system. The results of their recent study support further investigation into using...
by Ye Tian, Andrew Zalesky, University of Melbourne Brain scans acquired from 1000 people were used to map an atlas for one of the most evolutionarily ancient parts of the human brain. The most evolutionarily ancient part of our brain is the part that we know the least about. The human subcortex is located deep in...
by Dragana Mrkaja, La Trobe University Sepsis is caused by the immune system going into over-drive in response to infection. It leads to extreme inflammation that can cause blood clots and block oxygen from reaching vital organs, resulting in tissue death and multiple organ failure. Researchers from La Trobe University in Melbourne, Australia have identified and characterized...
by University of Pittsburgh Endowed Chair for Global Elimination of HIV and AIDS, and chief of the Division of Infectious Diseases at Pitt and UPMC. Increasingly, UPMC’s chief of infectious diseases—a well-regarded expert in HIV/AIDS—is contacted by a perplexed physician describing a patient with HIV who insists they are adhering to the daily medication regimen meant...
