NATIONAL RESEARCH COUNCIL OF SCIENCE & TECHNOLOGY IMAGE: ANTI-INFLAMMATORY ACTIVE MECHANISM IN SKIN CELLS. Ganoderma lucidum, known as Yeongji mushroom in Korea, is called a modern-day elixir plant and has long been used medicinally in China, Japan and Korea. Ganoderic acid, an active ingredient found in the mushroom, is known for its excellence in enhancing the immune...
KANAZAWA UNIVERSITY IMAGE: SUCLA2 GENE IS FREQUENTLY INVOLVED IN THE DELETION OF RB1 GENE REGION, WHICH OCCURS IN 10 – 30 % OF ADVANCED PROSTATE CANCERS. SUCLA2 DELETION GIVES RISE TO A METABOLIC. Kanazawa, Japan – The compound thymoquinone (TQ) selectively kills prostate cancer cells at advanced stages, according to a new study published in Oncogene....
TERASAKI INSTITUTE FOR BIOMEDICAL INNOVATION IMAGE: MICRONEEDLES FOR THERAPEUTIC GENE DELIVERY (LOS ANGELES) – There is great potential in gene therapy for treating certain types of cancer and genetic defects, immunological diseases, wounds and infections. The therapies work by delivering genes into the patients’ cells, which then produce therapeutic proteins to treat the affliction. When...
ALPHAMED PRESS IMAGE: NEUROPROTECTIVE EFFECTS OF HUMAN AMNIOTIC FLUID STEM CELL-SECRETOME IN AN I/R MODEL. Durham, NC – A study released today in STEM CELLS Translational Medicine points the way to a possible new avenue of treatment for ischemic stroke. The study, led by Annamaria Cimini, Ph.D., of the University of L’Aquila, and Liborio Stuppia, M.D., of...
WILEY Multiparametric magnetic resonance imaging of the prostate (mpMRIp) is a promising tool for diagnosing prostate cancer, and prior to its availability, detection relied on clinical exams and prostate specific antigen screening. In a study published in BJU International, investigators found that the availability of mpMRIp in Australia since 2012 has correlated with significantly reduced numbers of...
Knee osteoarthritis is a condition when the natural cushioning between knee joints (cartilage) wears away. Although it is commonly known as wear-and-tear arthritis, young people can get it too and it may even be hereditary. Knee osteoarthritis causes pain, which is usually addressed with paracetamol and nonsteroidal anti-inflammatory drugs. Now scientists from the University of...
In 2015, researchers began noticing that a drug used to treat Type 2 diabetes, empagliflozin, came with the added benefit of decreasing hospitalization for heart failure and death from cardiovascular causes in those patients. “It was very unexpected, because this drug is targeted and marketed for Type 2 diabetes, not heart failure,” said Kim Ho, a pediatrics...
by UT Southwestern Medical Center The mammalian cannabinoid receptors (CB1 and CB2) sense endogenous endocannabinoids and plant and synthetic cannabinoids to engender a response in the host that leads to decreased inflammation, intestinal motility and secretion, and increased appetite. Mammalian endocannabinoids are also sensed by a bacterial cannabinoid receptor to decrease virulence of enteric pathogens. Endocannabinoids,...
by Salk Institute Imagine that you’re late for work and desperately searching for your car keys. You’ve looked all over the house but cannot seem to find them anywhere. All of a sudden you realize your keys have been sitting right in front of you the entire time. Why didn’t you see them until now? Now,...
by McGill University A McGill-led multi-institutional research team has discovered that during memory consolidation, there are at least two distinct processes taking place in two different brain networks—the excitatory and inhibitory networks. The excitatory neurons are involved in creating a memory trace, and the inhibitory neurons block out background noise and allow long-term learning to take place. The...
