by University of Luxembourg An international collaboration involving researchers from the Luxembourg Center for Systems Biology (LCSB) at the University of Luxembourg established an association between inflammation and specific genetic mutations in Parkinson’s patients. The study, recently published in the scientific journal Brain, highlights two biomarkers that could be used to assess Parkinson’s disease state and progression. The results...
All life depends upon DNA repair and replication. In every human cell the essential ability to replicate and repair genomes depends upon the coordinated actions of the genome sequence. Flaws or mistakes in repair and cell cycle regulation can lead to defects in the structure of the DNA and can prevent the replication from functioning...
In an impressive proof-of-concept demonstration, an interdisciplinary team of scientists has developed a bioelectronic system driven by a machine learning algorithm that can shift the membrane voltage in living cells and maintain it at a set point for 10 hours. Every living cell maintains a voltage across the cell membrane that results from differences in...
by Heidelberg University Neurobiologists at Heidelberg University have discovered how a special receptor at neuronal junctions that normally activates a protective genetic program can lead to nerve cell death when located outside synapses. Their fundamental findings on neurodegenerative processes simultaneously led the researchers at the Interdisciplinary Center for Neurosciences (IZN) to a completely new principle for therapeutic agents....
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS IMAGE: FIELD AND PROVIDES ALL-INCLUSIVE ACCESS TO THE CRITICAL PILLARS OF HUMAN GENE THERAPY: RESEARCH, METHODS, AND CLINICAL APPLICATIONS. New Rochelle, NY, October 8, 2020–The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing...
POHANG UNIVERSITY OF SCIENCE & TECHNOLOGY (POSTECH) IMAGE: DESIGN OF THE BULK PNIPAAM NANOPORE-PATTERNED SURFACE. (A) DIAGRAM SHOWING THE THREE-STEP NANOREPLICATION PROCESS CONSISTING OF ALUMINUM ANODIZING, NICKEL NANOELECTROFORMING, AND UV NANOIMPRINTING. (B) SEM IMAGES (SCALE BAR: 500 NM). Stem cells are cell factories that constantly divide themselves to create new cells. Implanting stem cells in...
UNIVERSITY OF TAMPERE An international research team has discovered a principle that explains the metastasizing of prostate cancer. When cancer evolves within the prostate, multiple spatially intermixed cancer cell clones are created that may invade the organs surrounding the prostate. However, only one dominant cell clone spreads systemically in the body and creates metastases. In...
IT’S THE FIRST GENE-HACKING TOOL THAT TARGETS SPECIFIC CELLS. BY DAN ROBITZSKI A team of scientists have developed a new gene-editing tool that, for the first time, can target the specific cells or organs that doctors want edited — including specific areas of the brain. While testing on lab mice, the Tufts University biomedical engineers...
BY DAN ROBITZSKI A postmortem analysis of the bodies of people who died from COVID-19 revealed something alarming: About half showed signs of the coronavirus in their brains. The actual impacts of the neural infections seem mild at worst, according to research published Monday in The Lancet Neurology. But the revelation that the coronavirus can reach patients’ central nervous...
A new apparatus improves how we study the effects of aiming high-field terahertz radiation at cells, with implications for regenerative medicine Terahertz light pulses change gene expression in stem cells, report researchers from Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS) and Tokai University in Japan in the journal Optics Letters. The findings come thanks to a new...
