Reviewed by Emily Henderson, B.Sc.,Sep 28 2020 The research by the UPV/EHU-University of the Basque Country, in collaboration with Harvard University, has yielded highly encouraging results, and studies in animal models have already begun. The UPV/EHU’s NanoBioCel research group has for many years been developing systems enabling cells to be used as drugs. Cell therapy raises hopes for treating...
Fine-tuning stem cell metabolism prevents hair loss
by University of Cologne Cross-section of a skin biopsy showing hair follicles extending downwards from the skin surface. Low oxygen around the hair follicle stem cells activates Rictor signaling (phosphorylated Akt; in magenta) locally at this site. Cell nuclei are labeled in blue. A team of researchers from Cologne and Helsinki has discovered a mechanism that prevents hair...
Researchers identify ‘druggable’ signaling pathway that stimulates lung tissue repair
by Children’s Hospital of Philadelphia Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries. The findings, which were published today...
How zika virus degrades essential protein for neurological development via autophagy
UNIVERSITY OF MARYLAND In a study published in Autophagy, researchers at the University of Maryland (UMD) shed new light on how Zika virus hijacks our own cellular machinery to break down a protein that is essential for neurological development and cellular communication, getting it to “eat itself”. By triggering this process known as autophagy, Zika virus is able...
A city in Brazil where covid-19 ran amok may be a ‘sentinel’ for the rest of the world
So many people have gotten sick in Manaus that researchers say the virus is running out of people to infect. What happens when a major city allows the coronavirus to rage unchecked? If the Brazilian city of Manaus is any answer, it means about two-thirds of the population could get infected and one person in...
How hormone therapy slows progression of atherosclerosis
THE NORTH AMERICAN MENOPAUSE SOCIETY (NAMS) CLEVELAND, Ohio (September 28, 2020)–As one of the most common treatments for effectively managing menopause symptoms, hormone therapy (HT) is also known to provide multiple health benefits, including slowing the progression of atherosclerosis. A study based on Early Versus Late Intervention Trial With Estradiol (ELITE) data evaluated the underlying...
Newer Type 2 diabetes medications have heart and kidney disease benefits, too
AMERICAN HEART ASSOCIATION DALLAS, Sept. 28, 2020 — Two newer groups of medications prescribed primarily for Type 2 diabetes treatment (SGLT2 inhibitors and GLP-1 receptor agonists) could significantly reduce risks associated with chronic kidney disease (CKD) and heart disease. Based on analyses of the clinical trials through March 2020, a group of leading experts in diabetes, heart...
How important is sex to women as they age?
THE NORTH AMERICAN MENOPAUSE SOCIETY (NAMS) CLEVELAND, Ohio (September 28, 2020)–Despite a common belief that women lose interest in sex as they age, a new study demonstrates that a significant percentage of women continue to rate sex as important throughout midlife. The study also identified those factors affecting which women continue to value sex most....
Artificial intelligence platform diagnoses dystonia with high accuracy in 0.36 seconds
by Massachusetts Eye and Ear Infirmary A diagram of a the DystoniaNet platform’s process in diagnosing dystonia from MRI. Researchers at Mass Eye and Ear have developed a unique diagnostic tool that can detect dystonia from MRI scans, the first technology of its kind to provide an objective diagnosis of the disorder. Dystonia is a potentially...
Three-Step Approach May Help Relieve One of the Itchiest Vulvar Conditions
A three-step approach may help relieve itch in patients with lichen simplex chronicus, “one of the itchiest conditions that we ever see on the vulva,” an expert advised at the virtual conference on diseases of the vulva and vagina, hosted by the International Society for the Study of Vulvovaginal Disease. For some patients, such as those...