UNIVERSITY OF WÜRZBURG IMAGE: SCHEMATIC REPRESENTATION OF THE FUNCTION OF BATF3. IN THE UPPER HALF YOU CAN SEE THE PHYSIOLOGICAL FUNCTION AND THE CONSEQUENCES IF THIS FACTOR IS MISSING (KNOCKOUT). THE LOWER HALF SHOWS. After an infection of the human body with a pathogen, a cascade of reactions will usually be set into motion. Amongst...
Inflammatory gene provides clue to obesity risk
by University of Queensland A gene that helps to control inflammation increases the risk of obesity and could be turned off in mice to stop weight gain, a study from The University of Queensland has found. UQ Institute for Molecular Bioscience researcher Dr. Denuja Karunakaran said she was determined to unravel the links between inflammation and...
VirScan offers new insights into COVID-19 antibody response
by Brigham and Women’s Hospital Colorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19. A tool designed to detect viral history in a drop of blood has gotten an upgrade in the age of COVID-19. VirScan, a technology that can determine which of more than 1,000...
High-fiber diet, low level inflammation: Sidestepping the effects of radiation
by Annabel Mansfield, University of South Australia Loved or hated, the humble oat could be the new superfood for cancer patients as international research shows a diet rich in fiber could significantly reduce radiation-induced gut inflammation. Conducted by the University of Gothenburg, Lund University and the University of South Australia, the preclinical study found that dietary oat bran can offset...
Conversation quickly spreads droplets inside buildings
by John Sullivan, Princeton University To study the flow of exhaled material, researchers filmed the movement of a mist of tiny droplets illuminated by a laser sheet in front of a person speaking several different phrases adjacent to the sheet. With implications for the transmission of diseases like COVID-19, researchers have found that ordinary conversation creates a conical...
New drug targeting DNA repair shows promise in range of advanced cancers
by Institute of Cancer Research A new precision drug which stops cancer from repairing its DNA has shown promise in an early-stage clinical trial—highlighting the potential of a new class of drugs known as ATR inhibitors. The drug candidate, tested in humans for the first time, was shown to be well tolerated and stopped the growth of...
Senescent cells may be good when it comes to a bad injury
by Medical College of Georgia at Augusta University Dr. Raghavan Raju and research associates Drs. Xiaogang Chu and Lun Cai. Credit: Kim Ratliff, Production Coordinator, Augusta University It’s called senescence, when stressed cells can no longer divide to make new cells, and it’s considered a factor in aging and in some diseases. Now scientists have some of the...
Genetic risk of developing obesity is driven by variants that affect the brain
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES Over the past decade, scientists have identified hundreds of different genetic variants that increase a person’s risk of developing obesity. But a lot of work remains to understand how these variants translate into obesity. Now scientists at the University of Copenhagen have identified populations of...
Repeated pregnancy loss may be tied to the olfactory system
WEIZMANN INSTITUTE OF SCIENCE IMAGE: FMRI IMAGES SHOWING THE HYPOTHALAMUS REACTIONS TO BODY ODOR. THE LEVEL OF ACTIVITY IN WOMEN WITH REPEATED UNEXPLAINED PREGNANCY LOSS (PINK) WAS HIGHER THAN THAT OF WOMEN IN THE CONTROL. The odors we give off are a sort of body language – one that may affect our relationships more than...
Prostate cancer: immunotherapy offers hope
MEDICAL UNIVERSITY OF VIENNA IMAGE: PROSTATE CANCER IS THE SECOND MOST FREQUENT CANCER IN MEN WORLDWIDE. (Vienna, 29 September 2020) An antibody for treating advanced prostate cancer improves progression-free survival in patients with metastasised, castration-resistant prostate cancer. This is the finding of the long-term analyses of an international phase 3 clinical trial, recently published in...