Unchecked ivermectin use in the region is making it difficult to test the anti-parasite drug’s effectiveness against the coronavirus. Emiliano Rodríguez Mega Peru (a hospital in Iquitos shown here) has been one of the nations hit hardest by the COVID-19 pandemic. As much of the world waits for an effective vaccine to curb the COVID-19...
By Rich Haridy, October 20, 2020 The first stage of the trial will be infecting healthy volunteers with the virus to discover the lowest dose that consistently leads to the development of COVID-19 Researchers in the United Kingdom are set to undertake controversial human challenge trials to accelerate the testing of COVID-19 vaccines. The trials, planned to commence...
by Lynda De Widt, Mayo Clinic Mayo Clinic researchers, along with national and global collaborators, have developed a potential test for Machado-Joseph disease, or spinocerebellar ataxia type 3 (SCA3)—a disease that has no cure. They also have clarified the role of a gene target associated with the disease. The inherited disease is linked to a mutation in...
by University Health Network A depiction of the double helical structure of DNA. Its four coding units (A, T, C, G) are color-coded in pink, orange, purple and yellow. Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection. The work builds on Princess...
by Kerry Benson, Brown University As researchers and medical professionals work to develop new treatments for cancer, they face a variety of challenges. One is intratumor heterogeneity—the presence of multiple kinds of cancer cells within the same tumor. Often, these “mosaic” tumors include cells, such as polyploidal giant cancer cells, that have evolved to become aggressive and resistant...
by Massachusetts Institute of Technology All of the components in the sensor device are easy to mass-produce, so the researchers estimate that each device would cost around $10. People with amyotrophic lateral sclerosis (ALS) suffer from a gradual decline in their ability to control their muscles. As a result, they often lose the ability to speak,...
by University of Pittsburgh Associate professor of epidemiology, University of Pittsburgh Graduate School of Public Health. A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia—with the help of the right bacteria, according to a new discovery led by researchers at the University of Pittsburgh Graduate School of Public Health. Their study,...
by Bob Yirka , Medical Xpress A team of researchers affiliated with a host of institutions in China has found evidence of a gut microbe deficiency in children who develop autism spectrum disorder (ASD). In their paper published in the journal Science Advances, the group describes their study of gut microbes in ASD children and what they found....
by University of North Carolina at Chapel Hill School of Medicine University of North Carolina School of Medicine scientists have made a curious discovery about a well-known human protein that helps the immune system fight viral infections. The lab of Stan Lemon MD, and colleagues found that one class of viruses actually requires this protein to...
by University of Alberta Faculty of Medicine & Dentistry University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published today in Nature Communications. The research team led by Luc Berthiaume, cell biology professor in the Faculty of Medicine & Dentistry,...
