‘Long Covid’ could actually be split into four different syndromes, scientists today claimed. Thousands of survivors have reported being plagued by symptoms such as fatigue, shortness of breath, muscle pain and heart arrhythmias months after beating the disease. But scientists are still baffled by the lasting effects of coronavirus, likened to this generation’s polio. Academics at...
Protein injections into testes could treat male infertility
By Michael Irving, October 22, 2020 A potential new treatment for male infertility has been demonstrated in tests on mice. Male infertility is a serious issue, often caused by low sperm counts. Now, researchers at Seoul National University have developed a way to deliver nanoparticles loaded with certain proteins directly into the testes. In tests in mice,...
Plant compound reduces cognitive deficits in mouse model of Down syndrome
by NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development The plant compound apigenin improved the cognitive and memory deficits usually seen in a mouse model of Down syndrome, according to a study by researchers at the National Institutes of Health and other institutions. Apigenin is found in chamomile flowers, parsley, celery, peppermint and citrus fruits....
The unexpected repair function of neutrophils
by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) From left to right: Andrés Hidalgo, Iván Ballesteros, and Andrea Rubio. Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered that neutrophils, the most abundant cells of the innate immune system, have many more functions in the body than previously thought. This finding suggests...
Newly discovered mechanism controls cancer cell growth and metabolism
by Karolinska Institutet In a new study published in the journal Cell Death & Differentiation, researchers at Karolinska Institutet have conducted a translational study that identified a new mechanism for controlling the breakdown of glucose in several different cancer forms. The discovery could lead to new therapeutic strategies aimed to reduce cancer growth. A common problem with the current...
Clinical trial shows experimental drug safely slows progression of diabetic kidney disease
by University of Chicago Medical Center The findings, simultaneously published in the New England Journal of Medicine and presented at the American Society of Nephrology’s Kidney Week 2020 conference, show the investigational drug finerenone had tangible renal and cardiovascular benefits for patients with chronic kidney disease and type 2 diabetes. The 5,700-person phase III trial was led by...
New therapeutic approach against leukemia
by Max Planck Society Bone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Leukemia frequently originates from the so-called leukemic stem cell, which resides in a tumor promoting and protecting niche within the bone marrow. Scientists from the Max Planck Institute of Biochemistry in Martinsried, Germany, have found a new way to make...
Taking the itch out of cancer immunotherapy
by University of Tsukuba Using the body’s immune system to fight cancer has great potential, but can also bring serious side effects, including itchy and painful skin reactions. But now, researchers from Japan have found how these skin reactions happen, potentially leading to a way to prevent them. In a study published this month in Communications Biology, researchers from the University...
Researchers create human airway stem cells from patients’ cells
by Boston Medical Center For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients. Given that airway basal cells are defined as stem cells of the airways because they can regenerate the airway epithelium in response to injury, this study may help...
PTSD and alcohol abuse go hand-in-hand, but males and females exhibit symptoms differently
by The Scripps Research Institute Through intricate experiments designed to account for sex-specific differences, scientists at Scripps Research have collaborated to zero in on certain changes in the brain that may be responsible for driving alcohol abuse among people with post-traumatic stress disorder, or PTSD. In studies with rodents, researchers found that males and females exhibit their own distinct symptoms and brain...