Actin is among the most abundant proteins in cells, and it has many jobs—from giving the cell its very shape and structure to managing networks of proteins crucial to numerous cellular functions. Without it, the fragile fundamental unit of life would crumble. A good deal of actin’s activity is based on mechanical signaling; it appears...
Researchers at the University of Toronto have found evidence that neutrophil immune cell activity is the missing link connecting periodontal disease with heart disease, cancer and other inflammatory conditions – possibly including COVID-19. The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind the association...
by The Ohio State University Mark and Brenda Zimmer spend time together at their Lewis Center, Ohio home. Mark was diagnosed with ALS two years ago and actively participates in clinical research to find effective treatments for the neurodegenerative disease. Research led by investigators at The Ohio State University Wexner Medical Center provides new hope for recovery...
BOSTON UNIVERSITY SCHOOL OF MEDICINE (Boston)–Genetics and the environment (including psychiatric stress) may contribute to the pace of cellular aging, causing some individuals to have a biological age that exceeds their chronological age. Researchers from the National Center for PTSD at VA Boston Healthcare System and Boston University School of Medicine (BUSM) now have found that...
BY DAN ROBITZSKI Using graphene, a nanomaterial made of carbon that’s just one atom thick, scientists say they’ve made a cheap, more accessible antibody test for kidney disease. The goal, the University of Manchester researchers say in a press release, was to make a test that measures specific antibodies quickly at the doctor’s office, rather than in whatever...
An inexpensive, accessible and non-invasive therapy for diseases and injuries of the brain may be slowly emerging: tiny particles called extracellular vesicles (EVs). Unlike stem cell therapies for repairing brain damage — which can be unsafe when tested in humans — EVs may safely regenerate brain cells and reduce inflammation, according to a recent study...
by Andrea Greif, Leukemia & Lymphoma Society Bone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Patients participating in The Leukemia & Lymphoma Society’s (LLS) groundbreaking precision medicine Beat AML Master Clinical Trial had superior outcomes compared to acute myeloid leukemia (AML) patients who opted for standard chemotherapy treatment, according to findings...
by Tim Stephens, University of California – Santa Cruz Cryptochrome is one of four main clock proteins that drive daily biological rhythms. This illustration shows a “pocket” in the clock protein complex where binding of the “tail” of the cryptochrome protein helps regulate the timing of the biological clock. A new study by researchers at UC Santa Cruz...
by University College London Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Elevated risk of Parkinson’s disease among people with type 2 diabetes appears to be reduced by some medications used to treat their diabetes, finds a new study led by UCL researchers. The researchers are testing one of...
by Queen Mary, University of London A new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsiveness to disease modifying anti-rheumatic drugs (DMARDs). Rheumatoid Arthritis (RA) patients are commonly treated with disease modifying anti-rheumatic drugs (DMARDs) despite the fact that up to 50% of patients are unresponsive to treatment....
