by University of North Carolina at Chapel Hill A first-of-its-kind study shows the mouth is a robust site for infection and transmission of COVID-19, according to new research published Oct. 27 on the preprint server medRxiv. A team of researchers led by the University of North Carolina at Chapel Hill and the National Institute of Dental and Craniofacial...
Low dose of the medicine intravenous immunoglobulin decreases the effect of dangerous toxins during severe infections
by Emma Karlsso, Karolinska Institutet During necrotizing soft tissue infections ordinary bacteria infect our body, spread rapidly and cause tissue death. Treatment with antibiotics is not sufficient and infected tissue needs to be removed through surgery. 22% of people who suffer from this disease need to amputate a limb and 18% do not survive. A common...
Stem cells: new insights for future regenerative medicine approaches
INSTITUTO GULBENKIAN DE CIENCIA IMAGE: CHROMOSOME SEGREGATION IN A HUMAN INDUCED PLURIPOTENT STEM CELL. CENTROMERES IN GREEN AND DNA IN MAGENTA. Stem cells are considered one of the most promising tools in the field of regenerative medicine because they are a cell type that can give rise to all the cells in our bodies and...
Research lowers errors for using brain signals to control a robot arm
CHINESE ASSOCIATION OF AUTOMATION By measuring brain signals and implementing a clever feedback scheme, researchers from India and the UK have reduced the positional error in brain-controlled robot arms by a factor of 10, paving the way to greatly enhancing the quality of life for people suffering from strokes and neuro-muscular disorders. Brain-computer interfaces (BCI) have seen...
To measure the severity of COVID-19, researchers create a tool that can pull an elusive marker from human blood
When COVID-19 attacks, the immune system produces a cytokine, or protein, called Interleukin-6 (IL-6), whose concentrations can offer vital information about a patient’s level and stage of infection. But measuring the critical marker has been extremely challenging, given its nearly undetectable presence in the biological stew that makes up human blood. Existing technology has not...
Biochemists reveal the cause of Charcot-Marie-Tooth disease—too much of a good thing
Vanderbilt researchers—including Charles Sanders, associate dean for research and professor of biochemistry, and graduate student Justin Marinko—have illuminated the cause of Charcot-Marie-Tooth disease, putting them on the road to developing therapeutic approaches for the disease that affects one in 2,500 people. The discovery was published in the article “Direct Relationship Between Increased Expression and Mistrafficking of the Charcot-Marie-Tooth-Associated Protein PMP22” published in...
Scientists use clues in the human genome to discover new inflammatory syndrome
Researchers from the National Institutes of Health (NIH) have discovered a new inflammatory disorder called vacuoles, E1 enzyme, X-linked, autoinflammatory and somatic syndrome (VEXAS), which is caused by mutations in the UBA1 gene. VEXAS causes symptoms that included blood clots in veins, recurrent fevers, pulmonary abnormalities and vacuoles (unusual cavity-like structures) in myeloid cells. The scientists reported their...
Magnetic Field and Hydrogels Could Be Used to Grow New Cartilage
Instead of using synthetic materials, Penn Medicine study shows magnets could be used to arrange cells to grow new tissues. Using a magnetic field and hydrogels, a team of researchers in the Perelman School of Medicine at the University of Pennsylvania have demonstrated a new possible way to rebuild complex body tissues, which could result in more...
From fluffy to valuable: How the brain recognises objects
To recognise a chair or a dog, our brain separates objects into their individual properties and then puts them back together. Until recently, it has remained unclear what these properties are. Scientists at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig have now identified them – from “fluffy” to “valuable” –...
Research finds a problem with concept of herd immunity in COVID-19
By Dr. Liji Thomas, MD,Oct 28 2020 A recent study published on the preprint server medRxiv* in October 2020 suggests that arguments in favor of herd immunity are weakened by the fact that the steep increase in the number of COVID-19 deaths as a result of being exposed to the virus many times instead of once...