by Karolinska Institutet Credit: Unsplash/CC0 Public Domain Intake of a high-fat diet leads to an increased risk for obesity, type 2 diabetes, cardiovascular diseases and fatty liver. A study in mice from Karolinska Institutet in Sweden shows that it is possible to eliminate the deleterious effects of a high-fat diet by lowering the levels of apolipoprotein...
Release of serotonin from mast cells contribute to airway hyperresposivness in asthma
UPPSALA UNIVERSITY In asthma, the airways become hyperresponsive. Researchers from Uppsala University have found a new mechanism that contributes to, and explains, airway hyperresponsiveness. The results are published in the scientific journal Allergy. Some 10 per cent of Sweden’s population suffer from asthma. In asthmatics, the airways are hyperresponsive (overreactive) to various types of stimuli, such as cold...
Poor survival after heart attack linked to excess levels of signaling protein in heart
TEMPLE UNIVERSITY HEALTH SYSTEM (Philadelphia, PA) – About 6.2 million Americans suffer from heart failure, an incurable disease with a staggering mortality rate – some 40 percent of patients die within five years of diagnosis. Heart failure is one form of heart disease, for which new therapies are desperately needed. Now, in new work, scientists...
RNA analysis shows most SARS-CoV-2 variants rarely persist through secondary transmissions
by Bob Yirka , Medical Xpress Novel Coronavirus SARS-CoV-2 Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: National Institute of Allergy and Infectious Diseases, NIH A large team of researchers affiliated with a host of institutions across the U.K. has...
Antiphospholipid syndrome breakthrough: Cell-surface targets identified, opening path to therapies
by Bob Yirka , Medical Xpress The recognition of EPCR-LBPA by aPLs promotes autoimmunity. Credit: Science (2021). DOI: 10.1126/science.abc0956 A team of researchers affiliated with multiple institutions in Germany and the U.S. have found a cell-surface target for autoantibodies targeting phospholipids (aPL) that contribute to antiphospholipid syndrome (APS). In their paper published in the journal Science, the group describes how...
IBM develops AI to invent new antibiotics – and it’s made two already
By Michael Irving March 11, 2021 IBM has created an AI system that can find new antibiotic candidates quickly, to help fight the rising superbug threatphodopus/Depositphotos Hiding behind the current COVID-19 pandemic, another serious public health threat is looming – the rise of antibiotic-resistant “superbugs.” New antibiotics are needed to help turn the tide, but developing them...
Study provides insights into architecture of abnormal protein deposits in brain disorders
by Case Western Reserve University Credit: Unsplash/CC0 Public Domain Scientists at the Case Western Reserve University School of Medicine have determined the structure of protein “fibrils” linked to Lou Gehrig’s disease and other neurodegenerative disorders—findings that provide clues to how toxic proteins clump and spread between nerve cells in the brain. Their results may also lead...
How to make all headphones intelligent
RUTGERS UNIVERSITY IMAGE: ENGINEERS CONDUCTED EXPERIMENTS WITH “DUMB ” HEADPHONES WITH ESTIMATED PRICES RANGING FROM $2.99 TO $15,000. HEADFI CAN TRANSFORM SUCH HEADPHONES INTO SMART ONES. CREDIT: XIAORAN FAN How do you turn “dumb” headphones into smart ones? Rutgers engineers have invented a cheap and easy way by transforming headphones into sensors that can be...
Scientists discover cellular stress enzyme that might play key role in neurodegenerative diseases such as ALS
JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health. Overactivation of this type of stress response is a possible cause of injury to brain cells in neurodegenerative diseases such as Alzheimer’s,...
Study shows how reading skill shapes more than just reading
by Bert Gambini, University at Buffalo Credit: CC0 Public Domain A University at Buffalo researcher’s recent work on dyslexia has unexpectedly produced a startling discovery which clearly demonstrates how the cooperative areas of the brain responsible for reading skill are also at work during apparently unrelated activities, such as multiplication. Though the division between literacy and...