Month: <span>March 2021</span>

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High-fat diets can cause normal liver tissue to behave like tumor tissue
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High-fat diets can cause normal liver tissue to behave like tumor tissue

by  VIB (the Flanders Institute for Biotechnology) Credit: Unsplash/CC0 Public Domain Normal, non-cancerous liver tissue can act like tumor tissue when exposed to a diet high in fat, linking diet and obesity to the development of liver cancer. The Laboratory of Cellular Metabolism and Metabolic Regulation headed by Prof. Sarah-Maria Fendt (VIB-KU Leuven Center for Cancer...

Alzheimer’s disease proteins could be at fault for leading cause of vision loss among older people
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Alzheimer’s disease proteins could be at fault for leading cause of vision loss among older people

by  University of Southampton Credit: Unsplash/CC0 Public Domain Newly published research has revealed a close link between proteins associated with Alzheimer’s disease and age-related sight loss. The findings could open the way to new treatments for patients with deteriorating vision and through this study, the scientists believe they could reduce the need for using animals in future research into blinding...

New ‘Split-drive’ System Puts Scientists in the (Gene) Driver Seat
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New ‘Split-drive’ System Puts Scientists in the (Gene) Driver Seat

Powerful new genetic engineering methods have given scientists the potential to revolutionize several sectors of global urgency. So-called gene drives, which leverage CRISPR technology to influence genetic inheritance, carry the promise of rapidly spreading specific genetic traits throughout populations of a given species. Gene-drive technologies applied in insects, for example, are being designed to halt...

Lab identifies pathway for treating deadly melanomas
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Lab identifies pathway for treating deadly melanomas

Melanoma is the most aggressive and deadliest form of skin cancer. Effective treatments are elusive because one type of this cancer develops resistance to available inhibitors, and in another type, no effective drug treatment has yet been found. But a promising pathway to effective drug treatment of both types of melanoma has been identified by...

New mechanism of antibiotic tetracycline discovered
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New mechanism of antibiotic tetracycline discovered

Microbiologists from the University of Amsterdam’s Swammerdam Institute for Life Sciences (SILS-UvA), in collaboration with scientists from the AUMC, VU and the Chalmers University of Technology in Gothenburg, have discovered a thus far unknown mechanism of action of the antibiotic tetracycline, that has remained hidden in over 50 years of research on this compound. The team of...

Characterizing different cell types in the upper gastrointestinal tract
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Characterizing different cell types in the upper gastrointestinal tract

HUBRECHT INSTITUTE IMAGE: STAINING FOR KRT15 AND COL17A1 IN THE HEALTHY HUMAN ESOPHAGEAL EPITHELIUM CREDIT: GEORG BUSSLINGER, COPYRIGHT HUBRECHT INSTITUTE Researchers from the group of Hans Clevers identified and characterized rare cell types in the upper gastrointestinal tract. Using single cell RNA sequencing, they studied the cellular composition of the esophagus, stomach and upper part of...

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Charcot-Marie Tooth disease: A 100% French RNA-based therapeutic innovation

CNRS Charcot-Marie Tooth disease is the most common hereditary neurological disease in the world. It affects the peripheral nerves and causes progressive paralysis of the legs and hands. No treatment is currently available to fight this disease, which is due to the overexpression of a specific protein. Scientists from the CNRS, INSERM, the AP-HP and...

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Tropical cyclone exposure linked to rise in hospitalizations from many causes for older adults

COLUMBIA UNIVERSITY’S MAILMAN SCHOOL OF PUBLIC HEALTH An increase in overall hospitalizations was reported for older adults in the week following exposure to a tropical cyclone, according to a new study by researchers at Columbia University Mailman School of Public Health, Columbia University’s Earth Institute and colleagues at Colorado State University and Harvard T. H. Chan School...