by University of Göttingen Chronic 2-photon imaging of fluorescently labeled visual cortical neurons in the living adult mouse brain: within the first 4 days of imaging, from day 0 (d0) to day 4 (d4), one dendritic spine (white dendritic protrusion) was newly formed (green arrow); after selective visual stimulation over the next 4 days (until d8),...
Study shows vast potential of genomics-driven medicine approaches
Using cellular genomics, Garvan-led researchers have uncovered new links between DNA variants and cell gene activity. Researchers led by the Garvan Institute of Medical Research have made a crucial step forward in the understanding of how our own DNA information influences our personal disease risk, thanks to cutting-edge cellular genomics technology. By analysing the gene activity of 64,018 individual skin...
Biological artificial organs like skin, vessels…now produced more easily
NATIONAL RESEARCH COUNCIL OF SCIENCE & TECHNOLOGY IMAGE: OVERALL SCHEMATIC ILLUSTRATION OF THE FABRICATION OF EPUM USING PLCL USING A VIPS PROCESS DURING SPIN-COATING. THE FABRICATED MEMBRANE WAS TRANSFERRED TO A 12-WELL INSERT FOR CELL CO-CULTURE TO MIMIC AN ENDOTHELIAL BARRIER MODEL. CREDIT: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY(KIST) A Korean research group has developed a technology that allows...
Invasive weed may help treat some human diseases, researchers find
HIROSHIMA UNIVERSITY IMAGE: (A) BUD STAGE; (B) FLOWERING STAGE; (C) SPIKELETS CREDIT: QUAN, HIROSHIMA UNIVERSITY Native to the southeastern United States, a weedy grass has spread northward to Canada and also made its way to Australia and Japan. Andropogon virginicus grows densely packed and up to seven feet tall, disrupting growth patterns of other plants and competing...
Artificial intelligence reveals current drugs that may help combat Alzheimer’s disease
MASSACHUSETTS GENERAL HOSPITAL BOSTON – New treatments for Alzheimer’s disease are desperately needed, but numerous clinical trials of investigational drugs have failed to generate promising options. Now a team at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) has developed an artificial intelligence-based method to screen currently available medications as possible treatments for Alzheimer’s...
Oral COVID treatment yields promising trial data: drugmakers
Colorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19. Credit: NIAID Integrated Research Facility, Fort Detrick, Maryland. Pharmaceutical giant Merck and an American laboratory reported promising results Saturday in trials of a drug administered orally to fight COVID-19, saying it helps reduce patients’ viral load....
New insight to the brain’s response to injury
by Yale School of Engineering and Applied Science Credit: Pixabay/CC0 Public Domain In response to brain injury, neural stem cells cluster and migrate to the site of injury. The clustering is key—without it, the cells don’t travel. But what causes it? To investigate, Yale researchers created a 3-D model of the brain’s workings. The results of the...
Predicting pediatric seizures with a wristband
by Jessica Cerretani, Children’s Hospital Boston Credit: Children’s Hospital Boston The ability to track seizures has a number of potential benefits: It could allow physicians to better determine optimal dosing and timing of medication, as well as enable timely interventions to help prevent impending seizures. Traditionally, electroencephalography (EEG) and electrocorticography have been used to evaluate and...
Astrocytes derived from patients with bipolar disorder malfunction
Date: March 4, 2021 Source: Cell Press Brain cells called astrocytes derived from the induced pluripotent stem cells of patients with bipolar disorder offer suboptimal support for neuronal activity. In a paper appearing March 4th in the journal Stem Cell Reports, researchers show that this malfunction can be traced to an inflammation-promoting molecule called interleukin-6...
Everything You Need to Know Before Getting Your Second COVID-19 Vaccine Shot
Sonya Narla, DO February 9, 2021, 1:15PM (PT) Key takeaways: COVID-19 vaccine rollout varies widely from region to region, so being proactive and checking with your local health department is key. If you start with a particular vaccine, you need to get the second shot with the same vaccine. Taking ibuprofen or acetaminophen to help...