Month: <span>March 2021</span>

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IU researchers discover new potential for functional recovery after spinal cord injury
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IU researchers discover new potential for functional recovery after spinal cord injury

INDIANA UNIVERSITY SCHOOL OF MEDICINE IMAGE: FROM LEFT, WEI WU, PHD, AND XIAO-MING XU, PHD CREDIT: IU SCHOOL OF MEDICINE Researchers at Indiana University School of Medicine have successfully reprogrammed a glial cell type in the central nervous system into new neurons to promote recovery after spinal cord injury–revealing an untapped potential to leverage the cell...

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WRAIR, Duke scientists find evidence of monoclonal antibodies activity against malaria

WALTER REED ARMY INSTITUTE OF RESEARCH Scientists at Walter Reed Army Institute of Research, in a collaboration with Duke University, have confirmed that monoclonal antibodies can be an effective tool in the global fight against malaria.  The study, led by Dr. Sheetij Dutta, chief of the Structural Vaccinology Laboratory at WRAIR, showed that mAbs such as CIS43...

New molecular driver of frontal circuit maturation discovered
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New molecular driver of frontal circuit maturation discovered

THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE IMAGE: HIROFUMI MORISHITA, MD, PHD, ASSOCIATE PROFESSOR OF PSYCHIATRY, NEUROSCIENCE AND OPTHALMOLOGY AT THE ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI AND LEAD AUTHOR OF THE STUDY. CREDIT: MOUNT SINAI HEALTH SYSTEM Mount Sinai Researchers find a new way to prevent attention deficits associated with Fragile X,...

Rapid 3D printing method moves toward 3D-printed organs
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Rapid 3D printing method moves toward 3D-printed organs

by  University at Buffalo It looks like science fiction: A machine dips into a shallow vat of translucent yellow goo and pulls out what becomes a life-sized hand. But the seven-second video, which is sped-up from 19 minutes, is real. The hand, which would take six hours to create using conventional 3-D printing methods, demonstrates what...

Could transforming alpha cells into beta cells treat diabetes?
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Could transforming alpha cells into beta cells treat diabetes?

New research in mice suggests a novel way to treat both forms of diabetes. 1130945222 Tom Werner/Getty Images Scientists have used synthetic antibodies to block cell receptors in the liver that normally bind to glucagon, a hormone involved in increasing the amount of glucose in the blood. The antibodies restored normal blood glucose levels in three different...

HIV treatment helps prevent active TB
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HIV treatment helps prevent active TB

by  The Francis Crick Institute Credit: CC0 Public Domain Antiretroviral treatment (ART) reduces the risk of developing active tuberculosis (TB) in people also infected with HIV-1, by dampening the activation of the body’s immune response. These findings could help improve treatment for both conditions in the future. TB remains to be the leading bacterial cause of...

Huntington’s disease driven by slowed protein-building machinery in cells
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Huntington’s disease driven by slowed protein-building machinery in cells

by  The Scripps Research Institute Disease-causing huntingtin, shown in red, interacts with ribosomes, shown in green, in a striatal neuron. The nucleus is blue. Credit: Nicolai Urban of Max Planck Institute for Neuroscience in Jupiter, Florida. In 1993, scientists discovered that a single mutated gene, HTT, caused Huntington’s disease, raising high hopes for a quick cure. Yet today,...

How does your brain process emotions? Answer could help address loneliness epidemic
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How does your brain process emotions? Answer could help address loneliness epidemic

by  University of California – San Diego Credit: Unsplash/CC0 Public Domain Research over the last decade has shown that loneliness is an important determinant of health. It is associated with considerable physical and mental health risks and increased mortality. Previous studies have also shown that wisdom could serve as a protective factor against loneliness. This inverse relationship...

Engineered ‘off the shelf’ stem cells target breast cancer that metastasizes to the brain
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Engineered ‘off the shelf’ stem cells target breast cancer that metastasizes to the brain

by  Brigham and Women’s Hospital Tumor cells (red) stem cells (green) and DAPI (blue) Credit: Khalid Shah lab, Brigham and Women’s Hospital Approximately 15-to-30 percent of patients with metastatic breast cancer have brain metastasis (BM), with basal-like breast cancer (BLBC) metastasizing to the brain most frequently. The prognosis for BLBC-BM patients is poor, as the blood-brain...

Putting a protein into overdrive to heal spinal cord injuries
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Putting a protein into overdrive to heal spinal cord injuries

by  UT Southwestern Medical Center New spinal neurons converted from glia. Credit: UT Southwestern Medical Center Using genetic engineering, researchers at UT Southwestern and Indiana University have reprogrammed scar-forming cells in mouse spinal cords to create new nerve cells, spurring recovery after spinal cord injury. The findings, published online today in Cell Stem Cell, could offer hope for the...