by Luciana Constantino, FAPESP The use of CAR T-cells reprogrammed to “recognize” Cryptococcus spp. proved effective to combat the infection in vitro and in mice (pulmonary cryptococcosis; image: Wikimedia Commons) An innovative cell-based treatment for cancer has been found promising for the control of infections caused by fungi. A study published in the journal Cytotherapy reports that the use of...
by University of Texas M. D. Anderson Cancer Center Contrary to long-held beliefs, Type I collagen produced by cancer-associated fibroblasts does not promote cancer development but instead plays a protective role in controlling pancreatic cancer progression, reports a new study from researchers at The University of Texas MD Anderson Cancer Center. This new understanding supports novel therapeutic approaches...
by Cell Press Credit: Unsplash/CC0 Public Domain Brain cells called astrocytes derived from the induced pluripotent stem cells of patients with bipolar disorder offer suboptimal support for neuronal activity. In a paper appearing March 4th in the journal Stem Cell Reports, researchers show that this malfunction can be traced to an inflammation-promoting molecule called interleukin-6 (IL-6), which is secreted...
by Medical University of Vienna Credit: CC0 Public Domain Frequently occurring chronic skin inflammation like in atopic dermatitis (AD or neurodermatitis) and psoriasis have different causes such as genetic predisposition, stress or allergens. These frequently occurring skin diseases are mostly attributed by biomedical scientists to a disturbed immune system, although the noticeable thickening and flaking of...
by Texas Children’s Hospital Credit: CC0 Public Domain Many cognitive neurodevelopmental disorders are a result of too many or too few copies of certain genes or chromosomes. To date, no treatment options exist for this class of disorders. MECP2 duplication syndrome (MDS) is one such disorder that primarily affects boys and results from a duplication...
by Texas A&M University Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia Texas A&M University College of Medicine ressearchers have recently discovered that cytisine—a smoking cessation drug commonly used in Europe—reduces the loss of dopamine neurons in females. These findings provide potential evidence for...
by Georgia Institute of Technology Researcher Daryll Vanover works with the nebulizer he adapted to test a new mRNA-based treatment for flu and Covid-19. The team used mRNA technology to code for a protein called Cas13a that destroys parts of the RNA genetic code that viruses use to replicate in cells in the lungs. It was...
BFR FEDERAL INSTITUTE FOR RISK ASSESSMENT The vegan diet is on trend. How this type of diet affects health is the subject of scientific studies. In a new study from the German Federal Institute for Risk Assessment (BfR), the bone health of 36 vegans as well as 36 people following a mixed-food diet was determined...
DEUTSCHES PRIMATENZENTRUM (DPZ)/GERMAN PRIMATE CENTER IMAGE: DR. MARKUS HOFFMANN, SCIENTIST AT THE INFECTION BIOLOGY UNIT AT THE GERMAN PRIMATE CENTER (DPZ) – LEIBNIZ INSTITUTE FOR PRIMATE RESEARCH. CREDIT: KARIN TILCH There are no therapeutics available that have been developed for COVID-19 treatment. Repurposing of already available medication for COVID-19 therapy is an attractive option to...
IMIM (HOSPITAL DEL MAR MEDICAL RESEARCH INSTITUTE) Administering zinc supplements to covid-19 patients with low levels of this element may be a strategy to reduce mortality and recovery time. At the same time, it could help to prevent risk groups, like the elderly, from suffering the worst effects of the disease. These are the findings of a...
