Month: <span>March 2021</span>

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A Better Way to Zap Our Brains
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A Better Way to Zap Our Brains

By Kim Tingley Published Feb. 24, 2021 Updated Feb. 25, 2021 The brain is an electrical organ. Everything that goes on in there is a result of millivolts zipping from one neuron to another in particular patterns. This raises the tantalizing possibility that, should we ever decode those patterns, we could electrically adjust them to treat...

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Scientists find gene that could ‘stop one-third of all cancers from developing’

by Chris Melore CHICAGO, Ill. — Cancer can come in many forms and each one has a different, devastating impact on the body. On a genetic level however, many of these cancers are the same. A new study finds targeting one specific gene may stop one-third of all cancers from developing. Researchers in Chicago say they’re targeting the...

FDA-approved antidiarrhea drug can reverse resistance to chemotherapy in a mouse model of leukemia
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FDA-approved antidiarrhea drug can reverse resistance to chemotherapy in a mouse model of leukemia

by Adrienne Williamson , Medical Xpress This lighthearted cartoon, supplied by Chi Wai Eric So, PhD., illustrates the research’s key finding: the repositioning of a diarrheal drug for leukemia treatment. Credit: Emily Zeisig New research into one of the most common and difficult cancers to treat has revealed an effective route to mitigating chemotherapy resistance through the use...

Starvation turns slime moulds into multicellular organisms
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Starvation turns slime moulds into multicellular organisms

When the slime mold Dictyostelium discoideum, or Dicty for short, runs out of food, sulfur limitation drives its development from a unicellular to a multicellular organism. Researchers at the Max Planck Institute of Immunobiology and Epigenetics present the nutrient signaling pathways in this early eukaryote in great detail. Their results show how metabolism may have played a crucial...

Oxygen deficit makes nerve cells grow
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Oxygen deficit makes nerve cells grow

Oxygen deficit, also called hypoxia, in the brain is actually an absolute state of emergency and can permanently damage nerve cells. Nevertheless, there is growing evidence that to a certain extent, hypoxia can also be an important signal for growth. Together with scientists from the University Hospitals of Copenhagen and Hamburg-Eppendorf, researchers from the Max Planck Institute...

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Atherosclerosis can accelerate the development of clonal hematopoiesis, study finds

MASSACHUSETTS GENERAL HOSPITAL BOSTON — Billions of peripheral white blood cells are produced every day by the regular divisions of hematopoietic stem cells and their descendants in the bone marrow. Under normal circumstances, thousands of stem cells contribute progeny to the blood at any given time, making white blood cells a group with diverse ancestry. ...

CUHK unveils balance between two protein counteracting forces in hereditary ataxias
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CUHK unveils balance between two protein counteracting forces in hereditary ataxias

THE CHINESE UNIVERSITY OF HONG KONG IMAGE: PRPF19 DEGRADES THE DISEASE PROTEIN OF SCA3 AND ALLEVIATES ITS TOXICITY. EXOC7 PROTEIN RESTRAINS PRPF19 FROM FUNCTIONING THE DEGRADATION, CAUSING IT TO LOSE ITS BENEFICIAL EFFECTS ON SCA3. CREDIT: CUHK Collaborating with the University of Oxford, Professor Ho Yin Edwin Chan’s research team from the School of Life Sciences of...

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Deep brain stimulation and exercise restore movement in ataxia

BAYLOR COLLEGE OF MEDICINE New research from Baylor College of Medicine scientists shows that a combination of deep brain stimulation (DBS) and exercise has potential benefits for treating ataxia, a rare genetic neurodegenerative disease characterized by progressive irreversible problems with movement.  Working with a mouse model of the human condition, researchers at Baylor and the Jan and Dan Duncan...