SHINSHU UNIVERSITY IMAGE: SCHEMATIC DIAGRAM OF THE EFFECT OF CURCUMIN MEDIATED BY PPARA PATHWAY IN AAPOAII AMYLOIDOSIS MODEL MOUSE. view more CREDIT: COPYRIGHT © 2021, JIAN DAI Curcumin is a polyphenol compound produced by plants of the Curcuma longa species and has been reported to have many physiological activities, which include anti-oxidation, anti-inflammatory, anti-cancer, and anti-amyloid properties. However,...
UNIVERSITY OF SEVILLE Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumours. Their results point to the important role of the TRIM37 protein, whose absence explains the appearance...
by University of Nevada, Las Vegas Gary Kleiger’s lab on UNLV’s campus has been a hub of activity in recent years, playing a significant role in a new realm of drug discovery — one that could potentially provide a solution for patients who have run out of options. Pictured is a protein complex vital to Kleiger’s...
by Oregon Health & Science University Credit: CC0 Public Domain New research in mice published today in the journal Scientific Reports strengthens the growing scientific consensus regarding the role of the gut microbiome in neurodegenerative disorders including Alzheimer’s disease. The study, led by researchers at Oregon Health & Science University, found a correlation between the composition of the gut...
by West Virginia University A new study by Rashi Mehta—a researcher with the WVU School of Medicine and Rockefeller Neuroscience Institute—finds that focused ultrasound may induce an immunological healing effect in the brains of Alzheimer’s patients. Credit: Caylie Silveria/West Virginia University West Virginia University scientists used MRI scans to show what happens when ultrasound waves target...
by Biophysical Society A structure of an antibody, called Z004 (shown in purple), bound to the envelope domain III protein of Zika virus (shown in gold). Credit: Shannon Esswein. The Zika outbreak of 2015 and 2016 is having lasting impacts on children whose mothers became infected with the virus while they were pregnant. Though the numbers...
by UT Southwestern Medical Center Liver lobule structure, identifying the three zones. Credit: UT Southwestern Medical Center While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained a mystery. Now, research from the Children’s Medical Center Research Institute at UT Southwestern (CRI) has identified the...
by Hiroshima University Credit: Pixabay/CC0 Public Domain Who would have thought that a small basic compound like vitamin B6 in bananas or fish could be key to a robust response against COVID-19? Studies have so far explored the benefits of vitamins D and C and minerals like zinc and magnesium in fortifying immune response against COVID-19. But research on vitamin B6 has...
by University College London Credit: torstensimon, Pixabay, CC BY 2.0 These are the findings of a study, published as a research letter in The Lancet, of 51 UK healthcare workers, around half of whom had a previous laboratory-confirmed SARS-CoV-2 infection. It showed that a single dose of Pfizer/BioNTech’s RNA vaccine resulted in a significantly enhanced immune response against the virus, compared to...
Alison Snyder Clumps of brain cells grown in the lab provide a way to study the organ that is central to our species but is largely inaccessible in living people. Why it matters: Brain-related disorders — from autism spectrum disorders to schizophrenia to Parkinson’s disease — are a leading contributor to disability in people around the world. These...
