Using viruses instead of antibiotics to tame troublesome drug-resistant bacteria is a promising strategy, known as bacteriophage or “phage therapy.” Scientists at the National Institutes of Health have used two different bacteriophage viruses individually and then together to successfully treat research mice infected with multidrug resistant Klebsiella pneumoniae sequence type 258 (ST258). The bacterium K. pneumoniae ST258...
PLOS IMAGE: During a urinary tract infection, uropathogenic Escherichia coli (their DNA is marked in red) producing the genotoxin colibactin and forming bacterial communities within the superficial cells of the bladder (the nucleus of the cells is marked in blue, their cellular sugar content is marked in green), here six hours after a replicated infection...
GARVAN INSTITUTE OF MEDICAL RESEARCH Researchers at the Garvan Institute of Medical Research have discovered a new type of bone cell that may reveal new therapeutic approaches for osteoporosis and other skeletal diseases. The new cells, which the researchers term ‘osteomorphs’, are found in the blood and bone marrow, and fuse together to form osteoclasts, specialised cells that...
WILEY Although guidelines do not recommend use of opioids to manage pain for individuals with knee osteoarthritis, a recent study published early online in Arthritis Care & Research, an official journal of the American College of Rheumatology and the Association of Rheumatology Professionals, estimates that 858,000 Americans use opioids such as tramadol and oxycodone for...
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE Until recently, scientists believed that the primary cilium – an antenna-like structure found on the surface of most human cells – was largely vestigial and had little bearing on the day-to-day lives of human beings. But more recently, a relatively small number of people have been found to have...
UT SOUTHWESTERN MEDICAL CENTER IMAGE: LIVER SECTION IMAGES SHOWING FLUORESCENTLY LABEL HEPATOCYTES IN DISTINCT ZONES. EACH ROW IS A DIFFERENT STRAIN OF LINEAGE TRACING MOUSE. CREDIT: UT SOUTHWESTERN MEDICAL CENTER While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained...
By JOE PINKSTONE FOR MAILONLINE PUBLISHED: 13:06 EST, 25 February 2021 | UPDATED: 13:42 EST, 25 February 2021 Scientists have developed a method which changes how a person’s brain functions to boost confidence and eradicate fears. It is believed the technique may have the potential to treat psychological conditions such as post-traumatic stress disorder (PTSD), phobias and anxiety. Dubbed ‘Decoded neurofeedback’,...
UNIVERSITY OF BIRMINGHAM Smartphones could be used to scan people’s eyes for early-warning signs of glaucoma – helping to prevent severe ocular diseases and blindness, a new study reveals. Some of the most common eye-related diseases are avoidable and display strong risk factors before onset, but it is much harder to pinpoint a group of...
U.S. ARMY RESEARCH LABORATORY IMAGE: ARMY-FUNDED RESEARCHERS FINDS THAT SOLDIERS’ INCREASED RISK OF DEVELOPING ALZHEIMER’S DISEASE IS LIKELY ROOTED IN THE ALTERATIONS TO THE TINY CONNECTIONS BETWEEN NEURONS IN THE HIPPOCAMPUS INSTIGATED BY BLAST EXPOSURES CREDIT: UNC PEMBROKE RESEARCH TRIANGLE PARK, N.C. — Research shows that Soldiers exposed to shockwaves from military explosives are at a higher risk for developing...
UNIVERSITY OF ALBERTA IMAGE: Chemistry professor Chris Cairo co-led a study that identified a new mechanism responsible for the harmful buildup of plaque on artery walls that can restrict blood flow. The discovery also pinpointed new targets for drugs that could improve treatment for people with cardiovascular disease. (Photo: Richard Siemens) CREDIT: RICHARD SIEMENS Glycomics researchers at...
