UNIVERSITY OF WÜRZBURG IMAGE: VIOLET LIGHT TRIGGERS A SIGNALLING CHAIN IN THE LIGHT SENSOR PROTEIN SWITCH-CYCLOP, BLUE OR GREEN LIGHT STOPS THE CHAIN. AT THE END, THE PRODUCTION OF THE SIGNALLING MOLECULE CGMP IS REGULATED BY THE ENZYME GUANYLYL CYCLASE (GC). CREDIT: (PICTURE: SHIQIANG GAO / UNIVERSITY OF WUERZBURG) The unicellular green alga Chlamydomonas reinhardtii...
Scientists use nanotechnology to detect bone-healing stem cells
UNIVERSITY OF SOUTHAMPTON Researchers at the University of Southampton have developed a new way of using nanomaterials to identify and enrich skeletal stem cells – a discovery which could eventually lead to new treatments for major bone fractures and the repair of lost or damaged bone. Working together, a team of physicists, chemists and tissue engineering...
GlyNAC improves multiple defects in aging to boost strength and cognition in older humans
BAYLOR COLLEGE OF MEDICINE A pilot human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC – a combination of glycine and N-acetylcysteine as precursors of the natural antioxidant glutathione – could improve many age-associated defects in older humans to improve muscle strength and cognition, and promote healthy aging. Published in...
Machine learning helps spot gait problems in individuals with multiple sclerosis
by Lois Yoksoulian, University of Illinois at Urbana-Champaign Researchers Manuel Hernandez, left, Rachneet Kaur and Richard Sowers have developed a machine-learning algorithm that could help doctors spot gait problems in people with multiple sclerosis and determine if they are a result of the disease or healthy aging. Credit: L. Brian Stauffer Monitoring the progression of multiple sclerosis-related...
How neuronal cell death occurs in bacterial meningitis
by Karolinska Institutet Gram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domain Researchers from Karolinska Institutet, Karolinska University Hospital, and The Wenner-Gren Institute at Stockholm University have conducted research within the field of bacterial meningitis and found how bacteria interact with neurons, causing neuronal cell death. The results of their...
Research uncovers additional treatment option in prostate cancer
by Karolinska Institutet Credit: Unsplash/CC0 Public Domain The standard treatment for advanced metastatic prostate cancer (PCa) is androgen deprivation therapy (ADT). And even if this is efficient in the short term, 1/3 of PCa will become resistant to ADT and develop castration-resistant prostate cancer. A new study, by Karolinska Institutet and others, shows that estrogen receptor...
Inflammation-fighting protein could improve treatment of rheumatoid arthritis
by Judith Van Dongen, Washington State University Study authors Mahamudul Haque, Salah-Uddin Ahmed, and Anil K. Singh look at a protein array in their lab at the WSU Health Sciences Spokane campus. Credit: Cori Kogan, Washington State University Health Sciences Spokane New research led by scientists at Washington State University has found that a protein known as GBP5 appears...
Research reveals how the brain inhibits remyelination in MS and how to treat it
by Ellen Goldbaum, University at Buffalo The inflamed tissue environment following demyelination prevents recruitment of oligodendrocyte progenitor cells (OPC) (green) and halts their division (red). This can be overcome by treatment with PI-88, a modulator of the heparanome (Credit: Darpan Saraswat Two papers by University at Buffalo researchers reveal important new findings as to how regeneration of myelin...
Using photothermal nanoparticles and immunostimulators, this biomimetic formulation also achieves an efficient combination therapy against multiple types of cancer
by Chinese Academy of Sciences Schematic illustration of the platelet-based formulation and anticancer application in photothermal-immunological combined therapy. Credit: WEI Wei Tumor targeting and intratumoral penetration are longstanding issues for cancer therapeutics. Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and the University of Chinese Academy of Sciences (UCAS) have developed...
New Hands-Free Sneaker
EVA TESFAYE The GO FlyEase, Nike’s first hands-free shoe, hinges open and closed, so the wearer just needs to slip their foot in and push down in order to put it on.Nike Cooper Lewis wears his Nike FlyEase sneakers, which are designed to be quick and easy to get into, every day. “They’re really the...