Month: <span>October 2021</span>

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AI tool pairs protein pathways with clinical side effects, patient comorbidities to suggest targeted Covid-19 treatments
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AI tool pairs protein pathways with clinical side effects, patient comorbidities to suggest targeted Covid-19 treatments

GEORGIA INSTITUTE OF TECHNOLOGY IMAGE: THIS COLORIZED TRANSMISSION ELECTRON MICROGRAPH SHOWS SARS-COV-2 VIRUS PARTICLES (ORANGE), ISOLATED FROM A PATIENT. CREDIT: NIAID VIA NIH CREDIT: NIAID VIA NIH The symptoms and side effects of Covid-19 are scattered across a diagnostic spectrum. Some patients are asymptomatic or experience a mild immune response, while others report significant long-term...

Research breakthrough could mean better treatment for patients with most deadly form of brain tumor
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Research breakthrough could mean better treatment for patients with most deadly form of brain tumor

by  Queen Mary, University of London Glioblastoma under microscope with dyes. Credit: Brain Tumour Research Centre of Excellence at Queen Mary University of London. Scientists studying the most common and aggressive type of brain tumor in adults have discovered a new way of analyzing diseased and healthy cells from the same patient. Crucially, the work which...

Nontoxic drug delivery system could lead to effective therapies for currently untreatable cancers
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Nontoxic drug delivery system could lead to effective therapies for currently untreatable cancers

by  University of Massachusetts Amherst Fig. 1: The intracellular lifestyle of Salmonella is controlled by flhDC. a The design goals were to genetically engineer a bacterial vehicle that (1) synthesizes a protein drug (yellow/purple), (2) actively invades into cancer cells, and (3) releases drug, which escapes Salmonella vacuoles (SCVs, red). b, c Ninety-six hours after intratumoral...

Broad-spectrum malaria vaccine developed
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Broad-spectrum malaria vaccine developed

by  Griffith University FIG 1 Schematic of the P. yoelii 17X liposomal vaccine. The liposomal vaccine was prepared using thin-film hydration with a mannosylated lipid core peptide (“F3”) as described previously (22) and 3D(6-acyl) PHAD. The liposomes contained pRBCs killed by freeze-thawing. (Adapted from Al-Nazal et al. [42].). Credit: DOI: 10.1128/mBio.02657-21 Griffith University researchers are a step...

World’s first smart bandage detects multiple biomarkers for onsite chronic wound monitoring
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World’s first smart bandage detects multiple biomarkers for onsite chronic wound monitoring

by  National University of Singapore Credit: National University of Singapore A research team led by Professor Lim Chwee Teck from the National University of Singapore’s (NUS) Department of Biomedical Engineering and Institute for Health Innovation & Technology (iHealthtech), in collaboration with clinical partners from Singapore General Hospital, has developed a smart wearable sensor that can conduct...

‘Junk DNA’ is a double-edged sword, and the good side has anti-cancer potential
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‘Junk DNA’ is a double-edged sword, and the good side has anti-cancer potential

by  University of Rochester Medical Center Credit: Pixabay/CC0 Public Domain Rochester biologists show how selfish genetic elements that can cause tumors may also trigger the death of cancer cells. Selfish genetic elements were once thought to be merely parasites of the genome. But researchers at the University of Rochester have discovered that this so-called “junk DNA”...

Targeted drug shows activity against brain metastases in kidney cancer
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Targeted drug shows activity against brain metastases in kidney cancer

by  Dana-Farber Cancer Institute A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need. The drug, cabozantinib, is a tyrosine kinase inhibitor that attacks several targets in cancer cells....

Protein involved in heart development boosts stem cell strategy for heart repair
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Protein involved in heart development boosts stem cell strategy for heart repair

by  Temple University Credit: Unsplash/CC0 Public Domain With age, the human heart gradually loses its ability to repair itself following injury. Damage wrought by injuries such as cardiac ischemia and heart attack, which are associated with decreased oxygen levels in the heart, can cause the heart to function below normal capacity, making it difficult for patients...

Wounded cancer cells supercharge immune system to destroy tumors
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Wounded cancer cells supercharge immune system to destroy tumors

By Nick Lavars October 20, 2021 Scientists have discovered a new way to enhance the ability of T cells to fight tumorsMIT/iStockphoto Scientists at MIT have made a discovery that could expand the potential of immunotherapy, enabling it to treat wider variety of cancers. The breakthrough stems from a newfound ability to jump-start the body’s...

BBQ lighter, combined with microneedles, sparks breakthrough in COVID-19 vaccine delivery
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BBQ lighter, combined with microneedles, sparks breakthrough in COVID-19 vaccine delivery

by  Georgia Institute of Technology Georgia Tech researchers Saad Bhamla (left) and Mark Prausnitz (right) study the ePatch in the laboratory. Credit: Candler Hobbs, Georgia Tech Future vaccine delivery may rely on everyday items like BBQ lighters and microneedles, thanks to the ingenuity of a team of Georgia Institute of Technology and Emory University researchers. The...