by Massachusetts Institute of Technology Credit: CC0 Public Domain Immunotherapy is a promising strategy to treat cancer by stimulating the body’s own immune system to destroy tumor cells, but it only works for a handful of cancers. MIT researchers have now discovered a new way to jump-start the immune system to attack tumors, which they hope...
by Josh Barney, University of Virginia Credit: Pixabay/CC0 Public Domain Researchers at the University of Virginia School of Medicine have uncovered how problems in cortical microcircuits in the brain can trigger epileptic seizures. The researchers say that targeting the problem could lead to new treatments for a devastating form of the disease. UVA epilepsy researchers Eric...
by Institute of Cancer Research Credit: Unsplash/CC0 Public Domain Men who inherit an increased risk of cancer through “Lynch syndrome” could benefit from regular PSA testing from age 40 to detect early signs of prostate cancer, researchers believe. Lynch syndrome raises the risk of several cancer types including—most famously—bowel cancer, and affects 175,000 people in the...
by Carla K. Johnson In this September 2021 photo provided by NYU Langone Health, a surgical team at the hospital in New York examines a pig kidney attached to the body of a deceased recipient for any signs of rejection. From left are Drs. Zoe A. Stewart-Lewis, Robert A. Montgomery, Bonnie E. Lonze and Jeffrey...
by Regenstrief Institute Credit: CC0 Public Domain Depression is the second most disabling condition in the world, after pain, so screening and diagnosis are crucial to improving outcomes for patients, especially in light of the COVID-19 pandemic. Research from Regenstrief Institute and Indiana University School of Medicine shows that the Patient Reported Outcomes Measurement Information Systems...
by Utrecht University Dr. Saskia Braber. Credit: Utrecht University Nutrients can work in surprisingly similar ways as medicines. Pharmacologists from Utrecht University conclude that more knowledge of the similarities between food and medicines could help develop diets to combat diseases. A Mediterranean diet, high-fiber food, and whole fruits and vegetables are well-known elements of healthy nutrition....
by Karolinska Institutet Systemic antibody responses, inflammation markers and other clinical parameters in relation to COVID-19 severity during acute disease. (A) Plasma IgG and IgA responses (n=19 for mild, n=58 for moderate, n=58 for severe and n=12 for fatal) against N, S and RBD are shown together with the levels of (B) C-reactive protein and the...
by University of Oxford Credit: Unsplash/CC0 Public Domain Researchers at the University of Oxford have identified a drug that could ultimately help improve heart function in people with diabetes who have heart attacks. The drug, currently in clinical trials as a potential treatment for a form of anemia, could help diabetic hearts to recover and reduce their risk...
by Stony Brook University Whole-cell recordings of excitatory neurons in forelimb M1 were localized to L2/3 and L5. A, Schematic showing the anterior–posterior span of recorded slices, restricted to the forelimb area of M1. B, Recorded neurons were visualized with streptavidin labeling of biocytin and confirmed as excitatory by negative immunoreactivity for GAD67. GAD67 and merged...
by Melissa Rohman, Northwestern University A Wright’s stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0 A retrospective study led by Northwestern Medicine investigators found that the chimeric antigen receptor (CAR) T-cell immunotherapy drug tisagenlecleucel demonstrated safety and efficacy in pediatric patients with relapsed and refractory B-cell acute...
