by Steven Reinberg (HealthDay)—A common group of bacteria may be causing deadly pneumonia or anthrax-like disease among metalworkers in the southern United States, health officials report. The bacteria, called Bacillus cereus (B. cereus), naturally occurs in soil and dust. B. cereus can cause food poisoning and anthrax-like disease, but why it singles out welders and other metalworkers...
While the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise if dosing occurs intermittently and during a developmental-critical period. Mark Bear, Picower Professor of Neuroscience at MIT, recalls the “eureka moment” 20 years ago when he realized that a severe developmental brain disorder — fragile X syndrome —...
It is well established that excess visceral fat is harmful. This tissue is metabolically active, and generates increased chronic inflammation through numerous mechanisms: a greater number of senescent cells; signaling by fat cells that appears similar to that produced by infected cells; increased debris from dead and dying fat cells that provokes the immune system....
Zachary Brennan Senior Editor The FDA late Friday awarded Boehringer Ingelheim the first interchangeability designation for its Humira biosimilar Cyltezo, meaning that when it launches in July 2023, pharmacists will be able to automatically substitute the Boehringer’s version for AbbVie’s mega-blockbuster without a doctor’s input. The designation will likely give Boehringer, which first won approval...
Jeffrey Nau, Oyster Point Pharma CEO October 18, 2021 10:45 AM EDT PharmaFDA+ Oyster Point Pharma now has its first FDA-approved product — Tyrvaya. And the biotech has taken a unique route to get there by using an old drug with a storied past. The New Jersey biotech announced this morning that the FDA has...
Lisa Rapaport October 08, 2021 If eating certain things ― like pizza or French fries ― makes it impossible to sleep at night, it might be because the hefty dose of salt in these foods is disrupting your sleep rhythms. For decades, scientists have advised people to limit consumption of salty foods because of an increased risk...
by Pennsylvania State University Credit: Anna Langova/Public Domain Filling half of a child’s plate with fruits and veggies isn’t just recommended by the United States Dietary Guidelines, it also helps increase the amount of produce that kids end up eating, according to Penn State research. In a controlled feeding study, the researchers tested two strategies for...
Fever, headache, confusion, seizures, amputations or death. Meningitis is a very serious brain infection that can affect the body in many ways and needs to be treated within 24 hours of contracting the disease. The World Health Organization estimates that there are close to three million cases per year. Between the four main causes of...
by University of Turku A malignant migrating breast cancer cell. The cytoskeleton of the cell is shown in purple and the “circulating” integrins within the cell are in green. Credit: Paulina Moreno-Layseca and Turku Bioimaging A research group at the University of Turku, Finland, has discovered a completely new mechanism that cells use to circulate integrins...
by Kyoto University Graphical abstract. Credit: DOI: 10.1016/j.ymthe.2021.05.016 Cancer therapies have seen great development over the decades. Radiotherapies and chemotherapies have saved countless lives, but the latest arsenal, adoptive cell therapies (ACT), has stirred most excitement. In ACT, cells are processed to enhance their anti-cancer immune effects and injected into the patient. A new study by...
