The practice of calorie restriction, eating fewer calories while still obtaining sufficient micronutrients, is well demonstrated to reduce cancer risk in animal models, and also appears to improve outcomes in the case of an established cancer. This is similarly the case for practices such as intermittent fasting or fasting mimicking diets, the latter having undergone trials as an adjuvant therapy...
Cleveland Clinic study links gut microbiome and aggressive prostate cancer
CLEVELAND CLINIC IMAGE: CLEVELAND CLINIC RESEARCHERS HAVE SHOWN FOR THE FIRST TIME THAT DIET-ASSOCIATED MOLECULES IN THE GUT ARE ASSOCIATED WITH AGGRESSIVE PROSTATE CANCER, CREDIT: CLEVELAND CLINIC October 28, 2021, CLEVELAND: Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help...
How glycogen is linked to heat generation in fat cells
by University of California – San Diego Artistic rendering of a brown fat cell with nucleus in pink, mitochondria in purple, and yellow lipid droplets scattered throughout. Credit: Scientific Animations Humans carry around with them, often abundantly so, at least two kinds of fat tissue: white and brown. White fat cells are essentially inert containers...
Certain brain rhythms coordinate cognitive map in human spatial navigation
by Chinese Academy of Sciences (A) Object-location memory task; (B) Schematic depiction of firing fields for one grid cell (purple circle). More fields are crossed during six moving directions which are aligned with the grid (purple), translating to stronger brain activity. (C) Depiction of all electrode contacts in mPFC and EC (black circles) relative to...
Drugs designed for prostate cancer show promise for treating melanoma in men
by University of Pennsylvania Melanoma in skin biopsy with H&E stain — this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0 New research shows that testosterone promotes melanoma proliferation by activating a newly recognized nonclassical testosterone receptor in melanoma cells called ZIP9 (encoded by the SLC39A9 gene), a zinc transporter that is not...
Exploiting cancer’s sweet tooth to develop a treatment
by Jasmine Lee, Cold Spring Harbor Laboratory Credit: Unsplash/CC0 Public Domain Inositol is a sugar required for cells to survive. Most cells either get it from the bloodstream or make it themselves. Since there is plenty of inositol available, some cancer cells decide to stop making it. Cold Spring Harbor Laboratory Professor Christopher Vakoc and...
ALS and dementia attacked by an RNA-hunting compound that recruits cell’s own virus fighter
by The Scripps Research Institute To study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Credit: Jessica Bush, Disney Lab at Scripps Research, Florida One of the most commonly inherited forms of ALS and frontotemporal dementia is referred to as...
Psychologists create first-ever body-maps of hallucinations
by University of Leicester Credit: Pixabay/CC0 Public Domain University of Leicester psychologists have, for the first time, created body-maps of the sensations that arise during hallucinations in people experiencing psychosis. The study, published in The Lancet’s EClinicalMedicine, provides the most extensive descriptive data to date on the feelings that arise during hallucinations and where individuals reported...
Cheap antidepressant shows promise treating early COVID-19
by Carla K. Johnson This 2020 electron microscope image provided by the National Institute of Allergy and Infectious Diseases – Rocky Mountain Laboratories shows SARS-CoV-2 virus particles which cause COVID-19, isolated from a patient in the U.S., emerging from the surface of cells cultured in a lab. According to a study released in The Lancet Global...
How COVID-19 alters the immune system
by Ludwig Maximilian University of Munich Dendritic cell. Credit: D. Dudziak COVID-19 reduces the numbers and functional competence of certain types of immune cells in the blood, say LMU researchers. This could affect responses to secondary infections. The SARS-CoV-2 coronavirus causes moderate to severe disease in 3–10% of those infected. In such cases, the immune system...