by Ingrid Fadelli , Medical Xpress Credit: Coulibaly et. Oxidative stress is a condition resulting from an imbalance between the generation of reactive oxygen species (i.e., molecules containing oxygen with an uneven number of electrons) and the ability of antioxidants (i.e., molecules that can donate one electron to other molecules without becoming unstable) to neutralize...
by Jenni Ho, University of Kentucky Credit: CC0 Public Domain A new study from the lab of University of Kentucky Markey Cancer Director Mark Evers, M.D., demonstrates the critical role of the hormone neurotensin in cell proliferation and stem cell function in the small intestine. Recently published in Cellular and Molecular Gastroenterology and Hepatology, the study highlights...
by University of Otago Figure 1. Predicted GCSR difference in high anxiety cases. (a) Average GCSR over three classes of anxiolytic drug (ANX, N = 26) compared with placebo (PLA, N = 8). Data are from the same participants as we reported previously39, but with different analysis parameters matching those of the current paper and with...
by University of Michigan Credit: Unsplash/CC0 Public Domain Metformin, a drug commonly prescribed against diabetes, holds promise against a rare type of childhood brain tumor in laboratory studies, an international team of researchers led by the University of Michigan Health Rogel Cancer Center report in Science Translational Medicine. Experiments that uncovered new understandings of group A posterior fossa ependymomas—or...
by Johns Hopkins University Credit: CC0 Public Domain Vaping aerosols contain thousands of unknown chemicals and substances not disclosed by manufacturers, including industrial chemicals and caffeine, Johns Hopkins University researchers found. The study is the first to apply to vaping liquids and aerosols an advanced fingerprinting technique used to identify chemicals in food and wastewater. The...
by Robert Preidt and Ernie Mundell (HealthDay)—The rate at which homicide is taking the lives of Americans jumped by 30% over the first year of the COVID-19 pandemic—the largest year-to-year increase ever, new federal government figures show. The rate jumped from 6 homicides per 100,000 people in 2019 to 7.8 per 100,000 in 2020, according...
by Allen Institute for Brain Science Digital reconstructions of human neurons overlaid on a slice of brain tissue donated by a brain surgery patient. Allen Institute researchers are able to capture electrical information from these live human neurons, as well as their 3D shape and gene expression, through a technique known as Patch-seq. This image shows...
by University of California – Berkeley Brain slice from a transgenic mouse, in which genetically defined neurons in the cerebral cortex are labeled with a red fluorescent reporter gene. Credit: Tanya Daigle, the Allen Institute When you clicked to read this story, a band of cells across the top of your brain sent signals down your...
by NYU Langone Health Credit: CC0 Public Domain Cells that normally nourish healthy brain cells called neurons release toxic fatty acids after neurons are damaged, a new study in rodents shows. This phenomenon is likely the driving factor behind most, if not all, diseases that affect brain function, as well as the natural breakdown of brain...
by KU Leuven Researchers at the KU Leuven Rega Institute and CD3 have developed an ultrapotent inhibitor of the dengue virus, which causes the tropical disease known as dengue. The teams collaborated closely with Janssen Pharmaceutica, N.V. The antiviral molecule is exceptionally effective against all known dengue variants and could be used for therapeutic and prevention...
