by University at Buffalo Credit: Unsplash/CC0 Public Domain An investigation into the origins of the sensation of pain has led to the development of a novel and durable treatment for inflammatory pain that could be a promising alternative to opioids. The preclinical research was conducted by neuroscientists and pharmacologists, all in the Jacobs School of Medicine...
by European College of Neuropsychopharmacology Illustration: fMRI brain scans, showing the increased brain activity in the right angular gyrus in the prucalopride group versus the placebo group. Credit: Angharad De Cates. This illustration is licensed under Creative Commons Attribution 4.0 International License. The development of drugs to treat cognitive problems in patients with mental illness may...
by Cedars-Sinai Medical Center A new study led by Ruchi Mathur, MD, found that aging produces significant changes in the microbiome of the human small intestine. Credit: Cedars-Sinai Researchers at Cedars-Sinai have found that aging produces significant changes in the microbiome of the human small intestine distinct from those caused by medications or illness burden. The...
by American Physiological Society Credit: Nick Youngson CC BY-SA 3.0 Alpha Stock Images The findings of a new study indicate erectile dysfunction and inflammation could be prevented by blocking the effect of endothelin-1, which is a potent vasoconstrictor peptide and regulator of blood flow. A research team from Aarhus University in Denmark will present its findings virtually October 4–7...
by American Physiological Society Credit: Pixabay/CC0 Public Domain The results of three new studies indicate there could be new treatments for Alzheimer’s and stroke. One study reveals a possible link between gum disease and Alzheimer’s. Two other studies explore how the substance sovateltide shows promise for treating neurodegenerative disorders. The research data will be presented virtually...
by Mark Shrime, The Conversation Credit: Unsplash/CC0 Public Domain Early in the coronavirus pandemic, researchers stumbled on an unexpected finding: smokers seemed to be protected from COVID’s worst effects. Initially discovered on a review of hospitalized patients in China, this “smoker’s paradox” was later reported in studies from Italy and France. But it turns out that...
by Anna Zarra Aldrich, University of Connecticut Credit: Pixabay/CC0 Public Domain Any pain you experience is all in your head—really. When we feel pain in response to a stimulus, whether stubbing a toe, burning a finger, or something more severe, the feeling of pain is the result of a complex signaling pathway in the nervous system....
by Utrecht University, Utrecht University Researchers from Utrecht University coloured inhibitory brain cells (green), enabling the team to monitor how new brain cell connections arise. Credit: Utrecht University Whenever we learn, remember or forget something, a surprisingly active role is played by cannabis-like substances in the brain. Researchers at Utrecht University found that the substances actively...
by Tel-Aviv University Bone marrow pro-tumorigenic neutrophils (lower panel) promote the formation of new blood vessels (angiogenesis) in the tumor. GFP (green) = tumor, vWF (marker for blood vessels). Credit: Tel Aviv University A new Tel Aviv University study examined for the first time the development of a glioblastoma cancerous tumor in animal models with a...
EUROPEAN COLLEGE OF NEUROPSYCHOPHARMACOLOGY Type of research: not peer reviewed/experimental study/animal work Researchers have discovered that a particular protein can be used as a brain marker to indicate whether emotional memories can be changed or forgotten. This is a study in animals, but the researchers hope that the findings will eventually allow people suffering from...
