by University Hospital Tübingen Credit: CC0 Public Domain Did math problems make you stressed at school? That’s what happened to participants in a study of the brain’s reaction to stress. For the first time, researchers looked at the entire duration of such a situation. They found not only changes in the communication of brain regions,...
New research highlights clinical importance of interaction between immune cells in the lymphoma microenvironment
by University of Helsinki The figure shows immunostaining of lymphoma tissue rich in checkpoint proteins expressing macrophages. Credit: University of Helsinki Approximately 700 people are diagnosed with diffuse large B-cell lymphoma (DLBCL) in Finland each year. It is the most common cancer that originates from lymphocytes, immune system cells. Although the disease is treated with...
Finding a new biomarker and drug target in breast cancer
by Laurie Fickman, University of Houston Credit: CC0 Public Domain After examining 398 proteins, a University of Houston College of Pharmacy researcher has found one that is an important biomarker predicting therapy outcome and a potential drug target in estrogen receptor-positive (ER+) breast cancer, which makes up approximately 80% of all breast cancers. The growth...
E-cigarette use tied to respiratory symptoms, wheezing
(HealthDay)—Former and current electronic cigarette use is associated with higher odds of developing wheezing-related respiratory symptoms, according to a study published online Jan. 27 in the American Journal of Respiratory and Critical Care Medicine. Wubin Xie, Dr.P.H., from the Boston University School of Public Health, and colleagues assessed whether e-cigarette use is associated with the development of respiratory symptoms in young...
Does your child have asthma? Look for the signs
If you’re wondering whether your child may have asthma, there are some tell-tale signs to look for, an expert says. Asthma is the most common chronic respiratory disease in children and affects more than 6 million U.S. children. Despite being common, diagnosing asthma in children can be difficult because “there is no one-size-fits-all set of symptoms,”...
Study identifies key regulator of cell differentiation
by University of Illinois at Urbana-Champaign The research team included, from left, undergraduate student Darya Asoudegi; graduate students Neha Chetlangia and Fredy Kurniawan; and Supriya Prasanth, a professor of cell and developmental biology at the U. of I. Credit: L. Brian Stauffer Embryonic stem cells and other pluripotent cells divide rapidly and have the capacity...
The body fights infection amidst ‘waves’ of regulatory CD4+ T cells
by La Jolla Institute for Immunology In their proposed model of a Listeria infection, the LJI researchers show how two distinct groups of Tregs (bottom row) play different roles at different points in the infection. Credit: Published in Dolina et al., PNAS, and used with permission. Every kind of T cell has a job to do....
COVID-19 genetic risk variant protects against HIV
by Max Planck Society DNA analytics in the lab. Credit: Max Planck Institute for Evolutionary Anthropology The genetic variants we are born with can increase or decrease our risk of falling seriously ill with COVID-19. The major genetic risk variant for severe COVID-19, one we inherited from Neandertals, is surprisingly common. This raises the question...
Newly Discovered ‘Encrypted Peptides’ Found in Human Plasma Exhibit Antibiotic Properties
The rise of drug-resistant bacteria infections is one of the world’s most severe global health issues, estimated to cause 10 million deaths annually by the year 2050. Some of the most virulent and antibiotic-resistant bacterial pathogens are the leading cause of life-threatening, hospital-acquired infections, particularly dangerous for immunocompromised and critically ill patients. Traditional and continual...
Brainpower May Take A Beating Following Concussion
While mounting evidence indicates that the long-term effects of concussion include sleep disturbances, mood disorders and headache, a new study headed by UC San Francisco finds that it may also take a long-term toll on cognition. In the study, researchers found that a total of 13.5 percent of patients, who had been diagnosed a year...