by Queen Mary, University of London Performance of repeat expansion detection using whole genome sequencing (A) Swim lane plot showing sizes of repeat expansions predicted by ExpansionHunter across 793 expansion calls. Each genome is represented by two points, one corresponding to each allele for each locus, with the exception of those on the X chromosome...
Scientists pinpoint genetic target with promise for treating many forms of blindness
by Trinity College Dublin Figure 1. Spatial vision following rotenone insult. Rotenone was delivered bilaterally via intravitreal injection. Optokinetic responses were measured 2 months and 4 months post-injection using an OptoMotry virtual optokinetic system (Cerebral Mechanics). Bar charts represent the mean combined spatial frequency threshold. Error bars represent SD, ** p < 0.01, **** p...
Dendrites may help neurons perform complicated calculations
by Massachusetts Institute of Technology Credit: Pixabay/CC0 Public Domain Within the human brain, neurons perform complex calculations on information they receive. Researchers at MIT have now demonstrated how dendrites—branch-like extensions that protrude from neurons—help to perform those computations. The researchers found that within a single neuron, different types of dendrites receive input from distinct parts...
Bacteria in the nose may increase risk of Alzheimer’s disease
by Griffith University Schematics illustrating the process for quantifying the amount of viable infectious C. pneumoniae present in various mouse tissues. (A) Mice were first intranasally inoculated with C. pneumoniae (i), some with epithelial injury and some without. Following either 24 h, 3 days or 7 days or 28 days post inoculation, selected tissues were collected and homogenized in...
MRI may lower breast cancer deaths from variants in 3 genes
by University of Washington School of Medicine This screening MRI detected a very small cancer (circled) in the patient’s breast. Credit: Dr. Kathryn Lowry, Radiology, UW Medicine Annual MRI screenings starting at ages 30 to 35 may reduce breast-cancer mortality by more than 50% among women who carry certain genetic changes in three genes, according...
New imaging scan reveals a culprit in cognitive decline of Alzheimer’s
by Yale University PET scan of a human brain with Alzheimer’s disease. Credit: public domain Advanced imaging technology developed by Yale researchers has helped them confirm that the destruction of brain synapses underlies the cognitive deficits experienced by patients with Alzheimer’s disease, according to a study published Feb. 17 in the journal Alzheimer’s & Dementia. For...
Do low-carb diets help you lose weight? What the science says
by Clare Collins, Erin Clarke, Rebecca Williams, The Conversation Credit: Shutterstock In the 1970s, low-carb diets were all the rage. The Dr. Atkin’s Diet Revolution book claimed carbohydrate restriction was a “high calorie way to stay thin forever.” Carbohydrates are found in breads, cereals and other grains, fruit, vegetables and milk. They’re also in ultra-processed fast foods, cakes, chips...
How much exercise should disabled young people get? New recommendations offer advice
by Charlie Foster, Brett Smith, The Conversation Children and young people with disabilities should aim for between 120 and 180 minutes of aerobic activity a week. Credit: Daisy Daisy/ Shutterstock Being active is good for both physical and mental health. This is why evidence-based recommendations have long existed to advise people on how much exercise, and what type...
Study of LSD microdosing doesn’t show a therapeutic effect
by Ilima Loomis, University of Chicago Medical Center Credit: Pixabay/CC0 Public Domain Proponents of LSD “microdosing”—taking small amounts of the drug at regular intervals—claim it can improve mood and cognitive function. But new research by the University of Chicago has not found evidence to support those claims. Harriet de Wit, Ph.D., Professor of Psychiatry and...
Drooling is a common symptom of Parkinson’s. Could a workout for the swallowing muscles help?
by Naomi Cocks, The Conversation Credit: Shutterstock Imagine not wanting to leave your house because of fear you would drool. That’s the choice many people with Parkinson’s disease confront every day. Parkinson’s disease is the second most common neurodegenerative condition in Australia after dementia. It’s estimated around 70,000 Australians live with it and one of...