by University of Cologne Credit: Pixabay/CC0 Public Domain By investigating changes in the metabolic profile of neural stem cells, a research team led by Professor Dr. Matteo Bergami from the CECAD Cluster of Excellence for Aging Research at the University of Cologne discovered that the protein YME1L is essential in coordinating the shift between cellular...
Research team uncovers key brain mechanisms for organizing memories in time
by University of California, Irvine Credit: CC0 Public Domain In a scientific first, researchers at the University of California, Irvine have discovered fundamental mechanisms by which the hippocampus region of the brain organizes memories into sequences and how this can be used to plan future behavior. The finding may be a critical early step toward...
Intelligence is all about connectivity
by Julius-Maximilians-Universität Würzburg Credit: Pixabay/CC0 Public Domain You are just enjoying a nap on the sofa when your son suddenly turns up and asks you to help him with his math homework. This change from resting state to working mode is quite challenging for the brain. Based on the type of task, a specific neural...
Scientists have possibly cured HIV in a woman for the first time
By Benjamin Ryan An American research team reported that it has possibly cured HIV in a woman for the first time. Building on past successes, as well as failures, in the HIV-cure research field, these scientists used a cutting-edge stem cell transplant method that they expect will expand the pool of people who could receive similar...
Should serum or moisturizer go first in a skin care routine?
In most cases, it makes sense to apply serum before moisturizer. This is because serum is usually more lightweight, whereas moisturizer tends to be thicker. Applying serum first can also give the skin more opportunity to absorb the active ingredients. In many skin care routines, moisturizer is the last step. Below, we cover everything a person...
Promising new drug target to treat diabetes and other metabolic diseases
By Rich Haridy February 14, 2022 A newly discovered compound heightens the expression of a protein that helps regulate insulin secretion from the pancreas Depositphotos A new preclinical study has demonstrated how an experimental drug can treat type 2 diabetes by increasing the expression of a recently discovered protein found to influence insulin signaling in...
Study describes sequelae presenting more than six months after COVID-19 in non-hospitalized young adults
Reviewed by Danielle Ellis, B.Sc. A recent study posted to the medRxiv* preprint server described coronavirus disease 2019 (COVID-19) sequelae developed in non-hospitalized young adults more than six months after COVID-19 infection. Although extensive research has been conducted on the manifestation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) symptoms in infected patients, data about the persistence...
Improved Physical Function in Old Mice Treated with Rapamycin, Acarbose, and Phenylbutyrate
It is quite rare for researchers to attempt combined treatments, unfortunately. The panoply of calorie restriction mimetics and other approaches to gently upregulate stress responses are individually not all that impressive, and it remains unclear as to which of them can be stacked for greater effect. In the treatment of aging, even the better approaches that produce...
Male carriers of BRCA1 and BRCA2 gene mutation also at risk of multiple cancers
People who carry the BRCA1 or BRCA2 gene mutation have an increased risk of pancreatic, stomach and prostate cancers, as well as the previously well-known risk of breast and ovarian cancers – but not for melanoma, according to new University of Melbourne led research calling for increased testing in male carriers to detect the cancers early. The study used...
Amyloid Lurks in a Third of Cognitively Normal People Over 70
Including nearly 20,000 participants, the largest study on amyloid prevalence to date estimates that a third of cognitively normal people older than 70 have amyloid building up in their brains. Published January 31 in JAMA Neurology and led by Olin Janssen and Willemijn Jansen at Maastricht University in the Netherlands, the meta-analysis compiled amyloid PET and cerebrospinal fluid (CSF)...