Month: <span>February 2022</span>

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Restoring a deficient “motor” protein could improve fertility success
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Restoring a deficient “motor” protein could improve fertility success

By Michael Irving February 13, 2022 Researchers have identified a protein deficiency that may be behind many miscarriages and other chromosomal issuesDepositphotos The leading cause of miscarriage is that human eggs are surprisingly bad at managing the number of chromosomes in them. But now, researchers at the Max Planck Institute have identified a motor protein...

New test that can spot which prostate cancers are most deadly could save thousands of men from unnecessary treatment
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New test that can spot which prostate cancers are most deadly could save thousands of men from unnecessary treatment

By XANTHA LEATHAM FOR THE DAILY MAIL PUBLISHED: 20:08 EST, 13 February 2022 | UPDATED: 20:08 EST, 13 February 2022 A test that spots dangerous prostate cancer tumours has been developed by doctors. Current methods mean that differentiating between harmless and aggressive prostate tumours is incredibly difficult – especially at an early stage. For some men, the tumour can be...

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SCANS DON’T FIND MUCH DIFFERENCE IN BRAINS OF KIDS WITH OR WITHOUT ADHD

While providing little evidence of brain differences that are identifiable by MRI, the finding points to the need for more refined imaging techniques to better characterize the underlying biology of attention deficit hyperactivity disorder, which is diagnosed in an estimated 9% of children in the US. “There has been an ongoing debate dating back decades about whether...

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Mapping Mutation ‘Hotspots’ in Cancer Reveals New Drivers and Biomarkers

Researchers led by bioengineers at the University of California San Diego have identified and characterized a previously unrecognized key player in cancer evolution: clusters of mutations occurring at certain regions of the genome. The researchers found that these mutation clusters contribute to the progression of about 10% of human cancers and can be used to predict...

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Diabetes drugs could save thousands of lives

New research has linked two types of less-often prescribed diabetes drugs with lower chances of potentially fatal heart problems – including heart attack, heart failure and stroke – in people with type 2 diabetes without established heart disease. The study of English and Welsh data – led by University of Manchester and Manchester University NHS Foundation Trust (MFT) scientists, is published...

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Researchers identify potential therapeutic target for aortic stenosis

A Yale-led study provides new insights into the molecular and cellular development of supravalvular aortic stenosis (SVAS), a rare congenital heart defect caused by mutations or deletion of the elastin gene and characterized by narrowing of the aorta. The research, led by the Greif Lab in the Yale Cardiovascular Research Center, identified the role of the gene Notch3 in regulation...

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Study reveals neurobiological processes occurring during puberty that trigger sex differences in learning and memory

New findings suggest optimal teaching tactics, psychiatric treatment, should adapt to reflect brain differences. New research from the University of California, Irvine reveals that sex differences in learning and memory mechanisms are triggered by biological events occurring during puberty. Findings show prepubescent female rodents have much better hippocampal long-term potentiation (LTP) and spatial learning than...

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Bone growth inspired “microrobots” that can create their own bone

Inspired by the growth of bones in the skeleton, researchers at the universities of Linköping in Sweden and Okayama in Japan have developed a combination of materials that can morph into various shapes before hardening. The material is initially soft, but later hardens through a bone development process that uses the same materials found in the...

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A serendipitous finding lends new insight into how atopic dermatitis develops

UNIVERSITY OF PENNSYLVANIA Atopic dermatitis, a common skin condition affecting both children and adults, is often thought of as an inflammatory disease that arises from a breakdown in the barrier function of the skin. Now a new study pinpoints a cascade of inflammatory signaling that precedes the appearance of skin ulcers, shedding light on the...

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Study shows new drug combination more effective against SARS-CoV-2

UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE Researchers at the University of Maryland School of Medicine (UMSOM) and University of Pennsylvania Perelman School of Medicine have identified a powerful combination of antivirals to treat COVID-19. The researchers showed that combining the experimental drug brequinar with either of the two drugs already approved by the U.S. Food...