Month: <span>February 2022</span>

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Researchers introduce into human cells a genetic mutation that protects against Alzheimer’s disease
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Researchers introduce into human cells a genetic mutation that protects against Alzheimer’s disease

by Laval University Credit: Pixabay/Pete Linforth. Researchers from the Université Laval Faculty of Medicine and CHU de Québec–Université Laval Research Center have successfully edited the genome of human cells grown in vitro to introduce a mutation providing protection against Alzheimer’s disease. The details of this breakthrough were recently published in The CRISPR Journal. “Some genetic mutations increase the...

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Men with high levels of body fat may be at risk for osteoporosis

by  The Endocrine Society Men with high levels of body fat have lower bone density and may be more likely to break a bone than those with normal levels of body fat, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Most studies have shown positive or neutral effects of...

Study finds it safe to give clot-busting drug to stroke patients who took blood thinners
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Study finds it safe to give clot-busting drug to stroke patients who took blood thinners

by UT Southwestern Medical Center Credit: CC0 Public Domain Stroke patients on long-term blood thinners who were given the clot-busting drug alteplase enjoyed better recoveries than those who did not receive the drug and had no increased risk of bleeding, a new study led by UTSW researchers shows. The results run counter to the common...

From ‘super-recognisers’ to the ‘face blind’: How tests reveal underlying cognitive processes
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From ‘super-recognisers’ to the ‘face blind’: How tests reveal underlying cognitive processes

by Karen Lander, The Conversation ‘Have we met?’ Actor Brad Pitt thinks he is faceblind. Credit: Matteo Chinellato/Shutterstock The ability to recognize faces is important in many different real life contexts and fundamental to our social relationships and interactions. It allows us to identify people we care about, and respond appropriately to them. We may...

Challenges of deprescribing and minimizing use of anticholinergic medications
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Challenges of deprescribing and minimizing use of anticholinergic medications

by Regenstrief Institute Credit: CC0 Public Domain Medications with anticholinergic properties have been consistently associated with a wide range of adverse outcomes for older adults including cognitive impairment, yet these drugs continue to be commonly prescribed for depression, urinary incontinence, irritable bowel syndrome and Parkinson’s disease. In an editorial published in the peer-reviewed journal Frontiers...

A genetic difference affects the likelihood of severe COVID-19 infection
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A genetic difference affects the likelihood of severe COVID-19 infection

by Alex Dadswell, Imperial College London On the left, a solid representation of the three-dimensional structure of TMPRSS2 protein. On the right, a cartoon representation of the three-dimensional structure of the TMPRSS2 protein with an expanded view showing the switch from the amino acid valine (Val, top panel) to methionine (Met, bottom panel) caused by...

A machine-learning approach to managing diabetes and cardiovascular risk
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A machine-learning approach to managing diabetes and cardiovascular risk

by Elisabeth Reitman, Yale University Credit: CC0 Public Domain A novel online tool called INSIGHT offers a machine learning-based approach when prescribing sodium-glucose cotransporter-2 (SGLT2) inhibitors to maximize the benefit for patients with Type 2 diabetes. The study, led by Yale researcher Rohan Khera, MD, MS, appears February 4 in the journal Diabetes Care. The study’s first...