by King’s College London IMC image of a human colorectal cancer obtained with SIMPLI. Circled is a region with high-density of cytotoxic CD8 T cells and antigen-resenting macrophages. Magenta = tumor; red = CD8; cyan = B2M; green = CD68; blue = CD74. Credit: Lucia Montorsi A team of researchers from the King’s College London...
Tailoring collagen-based biomedical materials
by Thamarasee Jeewandara, Medical Xpress Conceptual scheme of the dynamically adaptive molten fibril state for collagen based on the electro-assembly pathway. (A) Illustration of hierarchical assembly of collagen over length scales via diverse interaction mechanisms, reversible interactions of hierarchical assemblies allow for structural reconfigurations and adaptive functions, and irreversible interactions allow yielding terminal structures that...
New research may pave the way to better treatments for Crohn’s disease
by Stony Brook University IL-17A acts on unique cell types to regulate intestinal function. Under normal conditions, IL-17A acts on stem cells to promote their differentiation into secretory epithelial cells. This visual depicts that during colitis, IL-17A acts on secretory cells to mitigate the disease’s inflammatory effects. Credit: Pawan Kumar A paper published this week...
“Revolutionary” pacemaker tackles heart failure by listening to the lungs
By Nick Lavars February 08, 2022 A new kind of pacemaker could change the way heart failure is treated, by adjusting heartbeats in response to breathing Depositphotos While modern pacemakers have proven an invaluable and lifesaving medical tool, the way they regulate the pace of the heart differs from the varying beat of the organ...
With CRISPR gene editing, unique treatments begin to take off for rare diseases
By Meeri Kim February 5, 2022 at 9:00 a.m. EST Paddy Doherty remembers his father as a proud, hard-working family man who stayed physically fit for most of his life. A career in construction and various home improvement projects kept him active until his 60s, when Doherty first caught glimpses of a worrying decline in...
THESE DATING APP TWEAKS COULD LEAD TO BETTER MATCHES
For couples in the US, meeting online is the most common first step toward coupledom. The internet officially edged out friends as the most effective matchmaker for straight Americans almost a decade ago—and for same-sex couples, several years before that. In two recent papers, Daniela Saban, an associate professor of operations, information, and technology at Stanford Graduate...
CAN ANTIHISTAMINES RELIEVE LONG COVID-19 SYMPTOMS?
That’s the conclusion of a case report on the experiences of two such patients cowritten by nursing scholars at the University of California, Irvine. The effects of COVID-19 on individuals range from mild symptoms to several weeks of illness to ailments including brain fog, joint pain, exercise intolerance, and fatigue that last for months after...
Advanced prostate cancer antibody drug shows success in pet dogs
Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research. In the first use of canines in an advanced prostate cancer study, scientists explored the pathways used by the cancer to evade the immune system and...
Brains of London cab drivers may help solve Alzheimer’s
The Knowledge – this is the name of a legendary test London taxi cab drivers need to take to be able to work in one of the largest and most significant cities in Europe. Despite the fact that we have easy access to satnav systems now, London cab drivers are required to know 25,000 street...
Scientists test promising biosensor aimed for use in brain
Scientists have successfully tested in the lab a tiny biosensor they developed that can detect biomarkers tied to traumatic brain injuries. In a study published recently in the journal Small, the Ohio State University researchers say their waterproof biosensor includes an “unprecedented combination of features” that may allow it to detect changes in the concentrations of various...