AMERICAN COLLEGE OF CARDIOLOGY Consumers are increasingly using smartwatches and other wearable devices to measure their heart rate and rhythm during exercise and for overall health monitoring. However, those measurements may be less accurate in people with darker skin tones, according to a study presented at the American College of Cardiology’s 71st Annual Scientific Session. The...
FDA approved new immunotherapy regimen for patients with melanoma based on Johns Hopkins Research
JOHNS HOPKINS MEDICINE FOR IMMEDIATE RELEASE The U.S. Food and Drug Administration has approved a novel therapy for patients with metastatic or inoperable melanoma, an aggressive type of skin cancer. The treatment, developed based on original research conducted at the Johns Hopkins Kimmel Cancer Center, is comprised of two immunotherapy agents, relatlimab (anti-LAG-3) and nivolumab...
New method of pancreatic islet cryopreservation marks breakthrough for diabetes cure
UNIVERSITY OF MINNESOTA IMAGE: RESEARCHERS AT THE UNIVERSITY OF MINNESOTA TWIN CITIES AND MAYO CLINIC WERE ABLE TO STORE TINY DROPLETS ENCAPSULATED WITH PANCREATIC ISLET CELLS AT VERY LOW TEMPERATURES FOR UP TO NINE MONTHS AND THEN USE NOVEL REWARMING TECHNIQUES TO BRING THEM BACK TO THEIR ORIGINAL STATE BEFORE TRANSPLANTATION. SHOWN IS ONE APPROACH...
Origins of diabetes may be different in men and women, according to new Concordia research
CONCORDIA UNIVERSITY IMAGE: KERRI DELANEY (LEFT) AND SYLVIA SANTOSA: “THE BIG QUESTION IS, HOW DO THE DIFFERENT FAT DEPOTS UNIQUELY CONTRIBUTE TO THE DEVELOPMENT OF DIABETES, AND IS THIS CONTRIBUTION DIFFERENT IN MEN AND WOMEN? CREDIT: CONCORDIA UNIVERSITY Over the past four decades, global cases of Type 2 diabetes mellitus have skyrocketed. According to the World...
Study finds complex relationships between bacteria and markers of lower airway infection and inflammation in cystic fibrosis
ANN & ROBERT H. LURIE CHILDREN’S HOSPITAL OF CHICAGO The lower airways of patients with cystic fibrosis (CF) have unique biochemical features that correlate with the complex communities of lung bacteria typical of this disease, according to a multicenter study led by researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago. These findings...
A new way to enter the cell using superchaotropic properties of boron clusters
CENTER FOR RESEARCH IN BIOLOGICAL CHEMISTRY AND MOLECULAR MATERIALS (CIQUS) IMAGE: CIQUS RESEARCHERS, PROF. JAVIER MONTENEGRO AND GIULIA SALLUCE. CREDIT: CIQUS The internalisation of impermeable molecules into cells is a current challenge in drug development, as many water-soluble bioactive molecules cannot cross the cell membrane. To facilitate the cell entry of these molecules, artificial transporters,...
Novel therapy could help people with asthma, COPD, cystic fibrosis and cancer-related lung disease
UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER HOUSTON ― A multicenter research team co-led by The University of Texas MD Anderson Cancer Center developed the first drug to treat the uncontrolled secretion of mucins in the airways, which causes potentially life-threatening symptoms in millions of Americans with asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis...
Discovery could pave way for new lung treatment
ANGLIA RUSKIN UNIVERSITY Scientists have discovered a new family of helpful proteins in the lung, with the finding potentially paving the way for a new course of treatment for patients with respiratory failure. Researchers from Anglia Ruskin University (ARU), alongside colleagues from Brown University and the Providence Veterans Affairs Medical Center in Rhode Island, US,...
A non-hormonal pill could soon expand men’s birth control options
by American Chemical Society A non-hormonal male contraceptive (known as YCT529; structure shown here) prevents pregnancy in mice by blocking a vitamin A receptor, with no obvious side effects. Credit: Md Abdullah Al Noman Women have many choices for birth control, ranging from pills to patches to intrauterine devices, and partly as a result, they...
Improving prognosis in chronic kidney disease
by Osaka University Figure 1. Overview of the present study. Credit: Tatsufumi Oka et al. Just as a water filtration system acts to filter contaminants from the water you drink, your kidneys act to filter waste and excess fluid from your blood. In chronic kidney disease (CKD), kidney function is impaired over time, and the...