by Mike Addelman, University of Manchester (a) Boxplot representing the permutation importance of the 56 proteins (from 215 cases; 230 controls) found to be significant by the Boruta algorithm. UniProt IDs are presented in Table 2. (b) Cumulative AUC for Boruta-identified biomarkers calculated from logistic regression analysis. Credit: Clinical Proteomics (2022). DOI: 10.1186/s12014-022-09345-1 Scientists have...
Kidney stones blasted by new non-surgical sound wave device
By Rich Haridy March 22, 2022 The ultimate goal of the research is to develop a small device that can be used in doctor’s offices and emergency rooms to easily treat kidney stones without surgery Depositphotos An article published in the Journal of Urology is reporting on the first 19 humans treated with a new non-invasive method...
New type of ultraviolet light makes indoor air as safe as outdoors
by Columbia University Irving Medical Center A new type of ultraviolet light that is safe for people took less than five minutes to reduce the level of indoor airborne microbes by more than 98%, a joint study by scientists at Columbia University Vagelos College of Physicians and Surgeons and in the U.K. has found. Even...
Cancer cells that spread to different sites in the body express varying levels of targetable proteins
by Massachusetts General Hospital Credit: Pixabay/CC0 Public Domain Cancer cells initially confined to a single location in the body can eventually spread, or metastasize, to distant sites such as the bone, lung, liver and brain, where they take on new characteristics depending on the particular tissue environment. In a study published in Cancer Research, a team...
How the gut communicates with the brain
by Flinders University Credit: Pixabay How the ‘second brain’ – the enteric nervous system in our gut—communicates with our first brain has been one of the most challenging questions faced by enteric neuroscientists, until now. New research from Flinders University has discovered how specialized cells within the gut can communicate with both the brain and spinal...
Researchers control brain circuits from a distance using infrared light
by Nicholas Weiler, Stanford University Illustration of experimental approach to stimulate TRPV1-expressing neurons using tissue-penetrating infrared light and amplifying MINDS molecules. Credit: Wu et al, Nature Biomedical Engineering (2022) DOI: 10.1038/s41551-022-00862-w Imagine the brain as a giant switchboard covered with thousands of buttons, knobs, dials and levers that control aspects of our thought, emotions, behavior, and memory. (You...
Heart attack survivors may be at greater risk of mental decline
by American College of Cardiology Credit: Pixabay/CC0 Public Domain A heart attack’s impact on the brain may be more serious than previously understood. About 1 in 3 heart attack survivors showed significant mental decline in the days and months following their heart attack, according to a study presented at the American College of Cardiology’s 71stAnnual...
Post-COVID psychosis occurs in people with no prior history. The risk is low but episodes are frightening
by Sarah Hellewell, The Conversation Credit: Pixabay/CC0 Public Domain Far from the respiratory disease it seemed at first, COVID can impact almost all parts of the body, including the brain. For a small number of people, COVID infection may be accompanied by an episode of post-COVID psychosis, a break from reality which can be frightening...
Neuronal mechanism that controls anxiety-like behavior and energy expenditure
by Li Yuan, Chinese Academy of Sciences Cav3.1-driven burst firing in ventromedial hypothalamic neurons exerts dual control over anxiety-like behavior and energy expenditure. Credit: SIAT Stress responses including physiological and behavioral changes facilitate threat avoidance. Long-term stress affects normal brain function and induces both anxiety and glucose or lipid metabolism disorders, leading to the development...
Brain implants allow fully paralysed man to communicate
“People have really doubted whether this was even feasible,” Mariska Vansteensel, a researcher at the University Medical Center Utrecht who was not involved in the study, told Science.org. The unidentified German man, 36, was diagnosed with ALS, a rare progressive nervous system disease that leads to the loss of muscle control, in 2015. When an ALS patient...