Many people with diabetes have times when they sweat too much, too little, or at odd times. Diabetes can make it difficult for a person’s body to maintain a steady temperature and produce the right amount of sweat to keep the body cool. Reasons for this include hormonal imbalances, cardiovascular factors, and stress. Diabetes can affect...
Antibody shows promise for developing hantavirus treatment
by US Army Medical Research Institute of Infectious Diseases Hantavirus particles display a characteristic square surface “lattice” made up of building blocks that contain the envelope glycoproteins Gn and Gc. These glycoproteins, which are the sole targets of neutralizing antibodies, control the virus’s ability to enter cells. Figure shows a schematic representation of the glycoproteins...
Elobixibat improves constipation in chronic kidney disease
For patients with moderate- to end-stage chronic kidney disease, elobixibat is associated with improvement in constipation and lipid metabolism, according to a study recently published in Frontiers in Medicine. Momoko Matsuyama, M.D., from Jichi Medical University in Saitama, Japan, and colleagues examined the effects of elobixibat on constipation and lipid metabolism among patients with moderate- to...
Factors associated with nonresponse to FMT identified in IBS
For patients with irritable bowel syndrome (IBS), those who are male and/or have low Alistipes levels are more likely to be nonresponders to fecal microbiota transplantation (FMT), according to a study published online March 18 in Neurogastroenterology & Motility. Magdy El-Salhy, M.D., Ph.D., from Stord Hospital in Norway, and colleagues included 109 patients who received allogeneic FMT...
Bidirectional association identified for NAFLD and psoriasis
There is a bidirectional association between nonalcoholic fatty liver disease (NAFLD) and psoriasis, especially for patients younger than 40 years, according to a study published online Feb. 16 in Frontiers in Immunology. Shuo-Yan Gau, from Chung Shan Medical University in Taichung, Taiwan, and colleagues retrieved data from Taiwan’s National Health Insurance Research Database to examine the...
Could sound waves help to regrow bones?
Interview conducted by Emily Henderson, B.Sc. Mar 21 2022 Thought Leaders Dr. Amy Gelmi Professor Leslie YeoRoyal Melbourne Institute of Technology (RMIT) In this interview, we speak to Dr. Amy Gelmi and Professor Leslie Yeo about their new research that is using sonic waves to turn stem cells into bone cells. Please can you introduce...
Brain studies show thousands of participants are needed for accurate results
Scientists rely on brain-wide association studies to measure brain structure and function—using MRI brain scans — and link them to complex characteristics such as personality, behavior, cognition, neurological conditions and mental illness. New research published in Nature from the University of Minnesota and Washington University School of Medicine in St. Louis is highlighting a path forward for brain imaging...
All of Us Research Program Releases First Genomic Dataset of Nearly 100,000 Whole Genome Sequences
Nearly 100,000 highly diverse whole genome sequences are now available through the National Institutes of Health’s All of Us Research Program. About 50% of the data is from individuals who identify with racial or ethnic groups that have historically been underrepresented in research. This data will enable researchers to address yet unanswerable questions about health and disease,...
BioAge’s oral drug prevents death from COVID-19 in old mice by reversing immune aging
BIOAGE LABS The immune system deteriorates with age, making COVID-19 particularly deadly in older people — but to date, no clinically available medication addresses this key risk factor. A study published today in Nature shows that an oral drug that reverses multiple aspects of immune aging effectively prevents death in a mouse model of COVID-19, suggesting...
Study shows that intranasal Rx halts memory decay in experimental Alzheimer’s model
LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER New Orleans, LA – A research collaboration between scientists at LSU Health New Orleans and the Karolinska Institutet in Sweden has found that applying specialized pro-resolving lipid mediators intranasally arrested memory loss and brain degeneration in an experimental model of Alzheimer’s Disease (AD). The results are published in the Nature journal, Communications Biology,...