WEILL CORNELL MEDICINE IMAGE: ART1 (IN GREEN) EXPRESSION IN TUMOR TISSUE FROM A LUNG CANCER PATIENT. CREDIT: SUMIT MUKHERJEE Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target for immunity-boosting cancer treatments, according to a study from researchers at Weill Cornell Medicine and Albert Einstein College...
Inhalable ‘aerogel’ triggers immunity to COVID-19 in mice, may block transmission
PENN STATE UNIVERSITY PARK, Pa. — An inhalable ‘aerogel’ loaded with DNA that encodes for the SARS-CoV-2 spike protein successfully induces an immune response against COVID-19 in the lungs of mice, according to new research conducted at Penn State. The team said its aerogel could be used to create an inhalable vaccine that blocks SARS-CoV-2...
What to know about Crohn’s disease in males
Crohn’s disease is a type of inflammatory bowel disease (IBD). Its incidence and the increased risk of other conditions or complications are different in males and females. Although symptoms and treatment may vary, these differ for each individual, rather than across age or gender. The Good Brigade/Getty Images Crohn’s disease is a chronic condition that causes...
3D matrix ultrasound accurately identifies cardiovascular injury in healthy individuals
by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) 3D model of a femoral artery obtained by real 3D imaging, revealing the location, number, and extent of distinct atherosclerotic plaques. In this sample, three plaques can be discerned (arrows), at the femoral bifurcation and distributed along the superficial branch. Credit: CNIC A new imaging technique...
Frailty may be reversible for some people with rheumatoid arthritis
by University of Glasgow Credit: Unsplash/CC0 Public Domain Rheumatoid arthritis patients living with frailty may find their frailty is reversible following treatment, according to a new study. The research, published in RMD Open and led by the University of Glasgow, looked at frailty—a vulnerability to poor health-outcomes—in people with rheumatoid arthritis (RA). The study used data...
Protein subunit COVID vaccine, which can be manufactured using engineered yeast, shows promise in preclinical studies
by Massachusetts Institute of Technology Novel Coronavirus SARS-CoV-2 Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: National Institute of Allergy and Infectious Diseases, NIH While many people in wealthier countries have been vaccinated against COVID-19, there...
Heartland virus identified in lone star ticks in Georgia
by Emory University Credit: Pixabay/CC0 Public Domain Heartland virus is circulating in lone star ticks in Georgia, scientists at Emory University have found, confirming active transmission of the virus within the state. The journal Emerging Infectious Diseases published the findings, which include a genetic analysis of the virus samples, isolated from ticks collected in central...
What regulates the ‘glue’ needed for nerve repair?
by University of Queensland Injured axons of the nematode C. elegans and other invertebrate species are able to rejoin with their separated segments, preventing degeneration and restoring the original axonal tract in a process known as axonal fusion. Ho et al. identify a metalloprotease of the ADAM family, ADM-4, as a key component necessary for...
Study finds direct effects of the coronavirus on long-term symptoms
by Hôpitaux Universitaires de Genève Graphical abstract. Credit: Journal of Internal Medicine (2022). DOI: 10.1111/joim.13482 Post-COVID illness is characterized by persistent symptoms of COVID-19 at least three months after an infection by SARS-CoV-2. Faced with the great diversity of symptoms and the emerging knowledge on the subject matter, the scientific and medical communities wish to better understand...
Study reveals how to activate the immune system’s natural killer cells to protect against cancer and other diseases
by Massachusetts General Hospital New research from Massachusetts General Hospital explains how natural killer (NK) cells’ interactions with extracellular matrix proteins regulate their function in solid organs, findings that could yield major therapeutic implications for cancer, viral infection, autoimmunity, and other inflammatory diseases. Here, NK cells (green) are embedded in collagen (red) rich matrix of...