by IOS Press Confocal microscope study of p-syn deposits in a dermal arteriole of a patient with Parkinson disease (A) and a patient with CBS (B). In both cases, most of the PGP9.5-stained fibers demonstrate the presence of p-syn as neuritic inclusions (arrowheads) shown by the merged image (scalebar 50 μM). Credit: Dr. Alex Incensi...
Adjuvant compared to early salvage therapy post-prostatectomy in men with PN1 prostate cancer decreased mortality risk
by Brigham and Women’s Hospital Credit: Unsplash/CC0 Public Domain Men with microscopic evidence of prostate cancer spreading to their pelvic lymph nodes (LNs) following the surgical resection of the prostate and pelvic lymph nodes (LN) are at a very high risk of dying from prostate cancer. Pelvic LN radiation therapy (RT) is a potentially curative...
New study shows pathogen and drug working together to fight fungal lung infection
by University of Maine Gram-stained P. aeruginosa bacteria (pink-red rods) Credit: Wikipedia Pathogens don’t always work against drug treatments. Sometimes, they can strengthen them, according to a new University of Maine study. Diseases caused by a combination of bacteria, viruses, fungi and parasites—also known as polymicrobial infections—are challenging to treat because scientists don’t fully understand...
The immune system is very complicated, but now, it’s on a chip
by Lindsay Brownell, Harvard University This illustration demonstrates the structure of the LF Chip: B cells and T cells were cultured together in the extracellular matrix (ECM)-lined lower channel, and were “fed” via the consistent flow of nutrient-containing medium through the upper channel. This flow is also what appears to have caused the spontaneous assembly...
What is the difference between chlamydia and gonorrhea?
Chlamydia and gonorrhea are sexually transmitted bacterial infections. A person can contract one of these infections if they have unprotected sexual contact with someone who has it. It can be hard to tell the difference between the two, as the symptoms can be similar. Chlamydia and gonorrhea are both extremely common. In 2018, chlamydia had...
Repairing cell structures altered by obesity restores metabolic function
By Nick Lavars March 14, 2022 A three-dimensional image of the interior of a diseased mouse liver cell shows alterations brought on by obesityHarvard University Improving our understanding of the impact obesity has on individual cells could go a long way to preventing some of its deleterious downstream effects, such as diabetes and cardiovascular disease....
TINY WATERMARKS COULD PROVE IF MEDICATION IS REAL OR NOT
Counterfeit medications and pharmaceutical products are just a click away from being purchased from online pharmacies. The new anticounterfeiting technology, however, can turn a smartphone into a lifesaver by simply taking a picture of a cyberphysical watermark and confirming if the medication is real or not. Young Kim, associate head for research and an associate...
Sliding into place: Study shows how cartilage interacts with the joints in our bodies
This new study sets the stage for improved treatments for bone diseases and injuries, and demonstrates a valuable new research tool. Cartilage is a fascinating substance. It coats the ends of our bones, allowing them to glide by one another at joints like our elbows and our knees. The surface it creates is about five...
Delayed recovery of consciousness is common for COVID patients on respirators
COLUMBIA UNIVERSITY IRVING MEDICAL CENTER March 15, 2022—Most patients with severe COVID who are put on ventilators regain consciousness following removal of respiratory support, but recovery may take weeks after the period of mechanical ventilation has ended, according to a new multicenter study. The study also found that patients took longer to recover consciousness the...
Researchers find out why yogurt lowers the risk of developing diabetes
UNIVERSITÉ LAVAL Québec City, March 15, 2022 – Scientists have known for some years that eating yogurt is associated with a reduced risk of diabetes, but the reasons behind this protective effect were unclear. A study published today in Nature Communications by researchers at Université Laval and Danone Nutricia Research reveals that this protection could come partly from...