by Eric Hamilton, University of Wisconsin-Madison Credit: Pixabay/CC0 Public Domain The antiviral therapies remdesivir, molnupiravir, and the active ingredient in Pfizer’s Paxlovid pill (nirmatrelvir), remain effective in laboratory tests against the BA.2 variant of SARS-CoV-2, the virus that causes COVID-19. The BA.2 variant also remains susceptible to at least some of the monoclonal antibodies used...
Rapid test delineates diseases with similar symptoms
by National Institutes of Health Duplex lateral flow assay for typhoid and malaria. Several drops of human serum are placed in the cartridge at the bottom. As the sample flows across the test strip in the cartridge, the red balls (nanoparticles) detect typhoid creating a red line and the blue nanoparticles detect malaria creating a...
Is there a difference between spondyloarthritis and ankylosing spondylitis?
Spondyloarthritis is a term used to describe a group of related inflammatory diseases that primarily affect the spine and other joints. Ankylosing spondylitis (AS) is a common type of spondyloarthritis. The main difference between spondyloarthritis and AS is that all cases of AS are a form of spondyloarthritis, but not all cases of spondyloarthritis are AS. The...
Relatlimab Plus Nivolumab a ‘Game Changer’ in Advanced Melanoma
Megan Brooks January 05, 2022 For untreated advanced melanoma, the fixed-dose combination of relatlimab and nivolumab is a “game changer that we have been waiting 10 years for,” Hussein Tawbi, MD, PhD, University of Texas MD Anderson Cancer Center, Houston, told Medscape Medical News about today’s publication of the phase 2/3 RELATIVITY-047 trial. Progression-free survival (PFS) was “essentially double” with...
Damage to inner ear system predicts fall risk among people with Alzheimer’s disease
by Johns Hopkins University School of Medicine Credit: Pixabay/CC0 Public Domain A Johns Hopkins Medicine study of about 50 people with Alzheimer’s disease has added to evidence that damage to the inner ear system that controls balance is a major factor in patients’ well-documented higher risk of falling. Overall, the researchers say, their study found...
Motor neuron toxin associated with ALS identified
by Jim Fessenden, University of Massachusetts Medical School Credit: Pixabay/CC0 Public Domain An international team of investigators has discovered that an inorganic polyphosphate released by nerve cells known as astrocytes in people with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) contributes to the motor neuron death that is the signature of these diseases. The...
Digital biomarkers identify bipolar disorder
Digitalisation plays a part in everything we do in our daily lives. Mountains of data collected from all our devices are a key ingredient in the digitalisation process. Health apps on our mobile phones, for example, record our unique behavioural and physiological data, and use that data to help us monitor and understand our own...
Researchers Examine Whether Virtual Reality Can Help Teens Regulate Emotions
A team of researchers in the school’s Department of Psychiatry, led by Justin Russell, PhD, research scientist in the Building Resilience to Adversity and Violent Experiences (BRAVE) Research Center, under the direction of Ryan Herringa, MD, PhD, associate professor of psychiatry, UW School of Medicine and Public Health, is examining how virtual reality can improve...
The Green Mediterranean diet modifies the bacterial population in our gut, with specific bacteria mediating weight loss and cardiac risk reduction
BEN-GURION UNIVERSITY OF THE NEGEV BEER-SHEVA, Israel, March 10, 2022 – The green Mediterranean diet (MED) has a striking effect on the microbial population of the human gut (i.e., the “gut microbiome”). In a large-scale clinical interventional trial- the DIRECT PLUS – the gut microbiome of green MED dieters was enriched with bacteria that are...
Could leaky blood vessels in the brain be a culprit in Alzheimer’s disease?
MEDICAL UNIVERSITY OF SOUTH CAROLINA IMAGE: A SCHEMATIC REPRESENTATION SHOWING SOME OF THE MAIN PLAYERS IN ALZHEIMER’S DISEASE. MODIFIED FROM “MONONUCLEAR PHAGOCYTES IN ALZHEIMER’S DISEASE” BY DAVID GATE AND OTHERS ON WIKIMEDIA COMMONS. CREATIVE COMMONS LICENSE 2.5: CREDIT: USE IN ACCORDANCE WITH THE CREATIVE COMMONS 2.5 LICENSE: CREATIVE COMMONS LICENSE Alzheimer’s disease is an enormous...