by Jennifer Reiley, Texas A&M University College of Engineering A digital view of a multicellular lymphangion-chip consisting of living co-cultures of lymphatic endothelial and muscle cells in 3D under flow. Credit: Dr. Abhishek Jain/Texas A&M Engineering Currently, there is little research focused on understanding mechanisms and drug discovery of lymphatic vascular diseases. However, conditions such...
by British Medical Journal Credit: CC0 Public Domain Shift work is linked to poorer working memory and slower mental processing speed, finds a pooled data analysis of the available evidence, published online in Occupational & Environmental Medicine. It is also associated with lower levels of alertness and visual focus, and the ability to control impulses and...
by Federico Graciano, Duke-NUS Medical School Graphical abstract. Credit: Journal of the American Society of Nephrology (2022). DOI: 10.1681/asn.2021040577 A treatment strategy using an antibody that inhibits a cell signaling protein called interleukin-11 (IL-11) could lead to new hope for people with a debilitating genetic kidney disease called Alport syndrome. Scientists from Duke-NUS Medical School, Singapore, reported...
by University of Otago Figure 1. H4 variants identified in the cohort. (A) Highly recurrent variants were found in six different H4 genes (H4C3, H4C4, H4C5, H4C6, H4C9, and H4C11), which all encode an identical protein. Aggregate prevalence of disease-causing amino acid changes is also shown. The N-terminal methionine is cleaved from histone H4, and therefore...
by Emily Head, Imperial College London Credit: Shutterstock Long-lasting immune activity in the airways might be the cause of persistent breathlessness following COVID-19. This is according to a new study of 38 people who were previously hospitalized with severe COVID-19. The results, published in Immunity, suggest these patients have an altered landscape of immune cells in their airways...
by Ludwig Maximilian University of Munich Graphical abstract. Upper left: schematic of the combined patient cohorts used. Upper right: Schematic of experimental setup. The study was divided into an exploratory cohort using scRNA-Seq, multidimensional flow cytometry of PBMCs, and shotgun plasma proteomics. The confirmation cohort was used to validate findings from the exploratory cohort, using...
by Madison Brewer, Carnegie Mellon University Mechanical Engineering Researchers investigate myoelectric signals—the electrical pulses associated with muscle contraction—to predict intended hand gestures. Credit: College of Engineering, Carnegie Mellon University For people with tetraplegia—a condition in which all four limbs have lost motor ability—regaining independence is a top priority. Although there is no cure for paralysis...
By LUKE ANDREWS HEALTH REPORTER FOR MAILONLINE PUBLISHED: 05:53 EST, 9 March 2022 | UPDATED: 07:23 EST, 9 March 2022 Becoming a mother at 50 could be the norm within the next decade, say scientists who have successfully ‘reverse-aged’ human eggs. In a major breakthrough, Israeli researchers effectively made eggs from 40 year old women resemble those of twenty-somethings. Women...
By WALLA! Published: MARCH 5, 2022 22:47 A man screams mid-exercise as he focuses during his workout (Illustrative)(photo credit: PIXAHIVE) There is a lot of noise in gyms; from different electronics blaring music, from people working out, from background music or music people listen to through headphones to drown out external sounds. Many group classes such as spinning, aerobics...
Jeff Craven February 17, 2022 Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The COVID-19 pandemic led to a decrease in the proportion of patients with rheumatic diseases who stopped taking their disease-modifying antirheumatic drugs (DMARDs), but the percentage who interrupted DMARD treatment increased later in the pandemic, according to...
