JOHN TIMMER – 3/8/2022, 5:44 PM Getty Images Infection by SARS-CoV-2 causes a dizzying array of symptoms beyond the respiratory distress that is its most notable feature. These range from intestinal distress to blood clots to the loss of smell, and symptoms vary wildly from person to person. Figuring out exactly what the virus does inside the...
by Ingebjørg Hestvik, Norwegian University of Science and Technology Why does inflammation occur in the blood vessels? Nathalie Niyonzima is one of the researchers who has uncovered an important cause. Credit: Ingebjørg Hestvik The underlying cause of many cardiovascular diseases is inflammation of the artery walls. Now NTNU researchers have found that a specific neurotransmitter...
by National Institutes of Natural Sciences Pain neuron-derived Reg3γ protects brain metabolism of LPS challenged mice. Credit: Kenta Maruyama A research team led by the National Institute for Physiological Sciences and joined by Hokkaido University explored the role of pain neurons in the regulation of endotoxic death. They found that peptide named Reg3γ acts as...
BY MITCH LESLIE 8 MAR 2022 10:00 AM A newly identified class of the human immune system’s T cells may kill other T cells, helping wind down attacks on infections and suppressing autoimmune conditions. DAVID SCHARF/SCIENCE SOURCE The price for a vigilant immune system that can pounce on tumor cells or pathogens is occasional friendly...
by Joe Dangor, Mayo Clinic Glioblastoma multiform – MRT T2 axial. Credit: Hellerhoff/Wikimedia Commons, CC BY-SA 3.0 Glioblastoma is an aggressive cancer that can occur in the brain or spinal cord. It can occur at any age, but glioblastoma is more common in older adults. The average age of diagnosis is 64. Also known as glioblastoma multiforme, glioblastoma...
by Wolters Kluwer Health Credit: CC0 Public Domain Service members who sustained combat-related traumatic brain injury (TBI) in Iraq or Afghanistan are at high risk of long-term disability—up to 49 times higher than in other groups of deployed veterans, reports a study in the March/April issue of the Journal of Head Trauma Rehabilitation (JHTR). “[W]e found...
by UT Southwestern Medical Center Stem-like cells (red) are generated from adult brain astrocytes. Credit: UT Southwestern Medical Center A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers report in a PNAS study. The findings might someday lead...
by Cell Press This graphical abstract depicts the findings of Nie, Li, and Li et al., who estimate biological ages of organs and systems using 402 multiomics features from 4,066 individuals and demonstrate several applications. They find that organs and systems are aging at different rates, and biological ages could be utilized for population stratification,...
by University of Zurich Network of astrocytes in the hippocampus of a mouse under the fluorescence microscope. Credit: Ladina Hösli, University of Zurich Astrocytes form large networks of interconnected cells in the central nervous system. When these cell-to-cell couplings are disrupted in the brain of adult mice, the animals are no longer able to store...
Researchers from Japan determine the precise mechanism of action of a β-1,2-glucan-associated enzyme, which offers fresh insights into complex sugar metabolism. Sugar chains confer functionality to many organic molecules in glycosides. Enzymes like glycosyltransferases catalyze the synthesis of these chains in various biological systems. However, the commercial production of carbohydrate chains involving enzymes that are...
