by Tokyo Medical and Dental University PRS of patients with severe radiographic progression was significantly higher than that of patients with non-severe progression. Credit: Department of Genomic Function and Diversity, TMDUPredicting the future may be beyond our grasp, but what about predicting disease progression? Researchers in Japan have delved into the human genome to investigate...
by Helmholtz Association of German Research Centres Red: Newly synthesized DNA. Credit: Helmholtz Zentrum München / Tsunetoshi Nakatani A totipotent cell is a single cell that can give rise to a new organism, if given appropriate maternal support. Totipotent cells have many properties, but we do not know all of them yet. Researchers at Helmholtz...
by Bob Yirka, Medical Xpress NE and 5HT levels in BLA start to decrease before NREM to REM sleep transition. Levels of NA and 5HT in the BLA showed a completely different pattern from that of DA. They were decreased during NREM sleep and started to further decrease just shortly prior to transition to REM...
by Cold Spring Harbor Laboratory In this image of the mouse brain, immune cells known as microglia (white) are seen interacting with other brain cells called chandelier cells (red) and pyramidal neurons (blue). This interaction helps pyramidal neurons grow the right connections during development. Credit: Nicholas Gallo/Van Aelst lab/CSHL, 2022 Microglia, the immune cells of...
Credit: CC0 Public Domain Helen McLaughlin says she was suffering so much that she would burn herself with a hot bottle “just because that was a nicer pain than the one that I was in”. But when her medical scans kept coming back clear, the doctors in London made her feel like “there’s nothing wrong...
by Hannah Messinger, University of Pennsylvania Credit: Pixabay/CC0 Public Domain At this point in the pandemic, it may not come as a surprise that the impacts of COVID-19 have included increases in mental health issues such as depression, anxiety, and substance use. Along with those issues, recent reports show that sleep has been impaired as...
FUJITA HEALTH UNIVERSITY IMAGE: THE HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K (HNRNPK) PLAYS MULTIPLE INHIBITORY ROLES IN SKELETAL MUSCLE CELL DIFFERENTIATION THAT IS BOTH MYOPARR-DEPENDENT AND -INDEPENDENT. CREDIT: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES RBPs (RNA-binding proteins) are a diverse category of proteins that are required for a wide range of cell activities. It’s worth noting that they...
MAX-PLANCK-GESELLSCHAFT IMAGE: IN ACUTE MYELOID LEUKEMIA, IMMATURE BLOOD CELLS DIVIDE UNCONTROLLABLY AND DISPLACE HEALTHY BLOOD CELLS IN THE BONE MARROW. CREDIT: ILLUSTRATION: SCIEPRO, ADOBE STOCK In order to better treat patients diagnosed with acute myeloid leukaemia (AML), researchers need to understand the pathological processes and distinguish between different subgroups of the disease. With the help...
ALBERT EINSTEIN COLLEGE OF MEDICINE March 7, 2022—(BRONX, NY)—A research team led by scientists at Albert Einstein College of Medicine has devised a novel and highly promising strategy for overcoming a key cause of cancer deaths: the ability of cancer cells to thrive in the face of chemotherapy drugs designed to destroy them. As described in the...
LEIBNIZ INSTITUTE FOR NATURAL PRODUCT RESEARCH AND INFECTION BIOLOGY – HANS KNOELL INSTITUTE Jena. Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years. A research team led by immunologist Christina Zielinski discovered this phenomenon by examining patient samples after stem cell transplantation. In...
