RUTGERS UNIVERSITY IMAGE: RUTGERS RESEARCHERS HARNESSED AI AND ROBOTICS TO DELIVER NEW HOPE FOR PATIENTS WITH SPINAL CORD INJURIES. CREDIT: PHOTO COURTESY OF RUTGERS SCHOOL OF ENGINEERING By employing artificial intelligence (AI) and robotics to formulate therapeutic proteins, a team led by Rutgers researchers has successfully stabilized an enzyme able to degrade scar tissue resulting...
Symptom persistence during first year following traumatic brain injury
by Mary Ann Liebert, Inc Number of symptoms endorsed at any severity by traumatic brain injury (TBI) severity subgroup and time. mTBI, mild TBI (admission Glasgow Coma Scale score 13–15); msTBI, moderate or severe TBI (admission Glasgow Coma Scale score 3–12). Credit: Journal of Neurotrauma (2022). DOI: 10.1089/neu.2021.0348 More than 70% of patients with traumatic brain injury...
Black adults may be at higher risk of diabetes due to genetic variations and social health determinants
by Anna Jones, University of Alabama at Birmingham 3D-model of DNA. Credit: Michael Ströck/Wikimedia/ GNU Free Documentation License In a recent study published in Circulation: Genomic and Precision Medicine, University of Alabama at Birmingham researchers found that, while many African Americans, especially those with a higher African ancestry proportion, have a favorable lipid profile, they are...
How a touch-sensing protein could stop constipation
by Flinders University Credit: Pixabay When we eat food, our gut somehow senses its presence to begin shifting it along our digestive tract, but the question has always been—how? Now, new Flinders University research using both human gut samples and mice has discovered that a touch-sensing protein that was a focus of a 2021 Nobel...
Potassium channel dysfunction in genetic epilepsy
by Will Doss, Northwestern University Figure 1. Functional analysis of KCNQ2/KCNQ3 channels by automated patch clamp. A) Screen display from automated patch clamp experiment illustrating whole-cell current recordings from CHO-Q3 cells transiently expressing KCNQ2 variants (6 variants, 4 columns per variant). B) Averaged XE991-sensitive whole-cell currents recorded from non-transfected CHO-Q3 cells, and CHO-Q3 cells electroporated...
Scientists develop gel that delivers drugs directly to diseased joints
Osteoarthritis (OA) is a progressive condition affecting the lives of more than 32 million Americans. Post-traumatic osteoarthritis (PTOA), a major subset of osteoarthritis that comprises 10% of diagnoses and disproportionally affects injured military personnel, has no effective therapeutic protocols that slow or stop the progression except for over-the-counter analgesics. Post-traumatic osteoarthritis leads to articular cartilage...
Unable to recognise rhythm or pitch: this is amusia
Not being able to recognise a well-known melody without the lyrics, not hearing whether someone is singing out of tune and not being able to produce a rhythm; for some people musicality is not their strongest point. For a small section of the population, this inability goes very far: they suffer from the disorder congenital amusia....
Is it working? Scientists say gene variant indicates effectiveness of immunotherapy for allergies
UNIVERSITY OF FUKUI IMAGE: ALMOST ONE THIRD OF THE POPULATION OF JAPAN IS ALLERGIC TO POLLEN FROM JAPANESE CEDARS. ALTHOUGH IMMUNOTHERAPY CAN GREATLY ALLEVIATE THE SYMPTOMS IN MOST PATIENTS AFTER PROLONGED TREATMENT, A CONSIDERABLE PERCENTAGE STILL DO NOT RESPOND FAVORABLY. CREDIT: THIS IMAGE WAS MARKED WITH A CC BY-SA 2.0 LICENSE. FOR REUSE, CREDIT THE...
Dirt can modulate the pathology in Alzheimer’s disease
by Kyoto University Credit: Kyoto University Eating well, exercising regularly, and having a satisfying social life are all crucial to staying healthy. Sometimes, however, it can be the tiniest things that make the biggest difference. In this case, those tiny things are microorganisms, such as bacteria and fungi. The metabolites they release can have profound...
Death toll nears 6 million as pandemic enters its 3rd year
by David Rising Registered nurse Rachel Chamberlin steps out of an isolation room where Fred Rutherford recovers from COVID-19 at the Dartmouth-Hitchcock Medical Center, in Lebanon, N.H., Monday, Jan. 3, 2022. The official global death toll from COVID-19 is on the verge of eclipsing 6 million—underscoring that the pandemic, now in its third year, is...