by Weill Cornell Medical College Illustration of the complex structure of S1P1, siponimod, and the Gi protein. The structure gives insights into how the drug activates the receptor. Credit: Dr. Xin-Yun Huang Investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets, a finding that may...
by Garvan Institute of Medical Research Dr Ira Deveson of the Garvan Institute of Medical Research. Credit: Garvan Institute of Medical Research A new DNA test, developed by researchers at the Garvan Institute of Medical Research in Sydney and collaborators from Australia, UK and Israel, has been shown to identify a range of hard-to-diagnose neurological...
PLOS IMAGE: STUDY DESIGN SCHEMATIC: GRAPHICAL OUTLINE OF THE COHORT STUDY TO ASSESS FUTURE TYPE 2 DIABETES AND CARDIOVASCULAR DISEASE RISK BY INTEGRATING GENETICS, LIPIDOMICS AND STANDARD CLINICAL DIAGNOSTICS. CREDIT: LIPOTYPE (CC BY 4.0, HTTPS://CREATIVECOMMONS.ORG/LICENSES/BY/4.0/) Simultaneous measurement of dozens of types of fats in the blood (“lipidomics”) can predict the risk of developing type 2 diabetes...
POHANG UNIVERSITY OF SCIENCE & TECHNOLOGY (POSTECH) IMAGE: PULSE SIGNAL MAP CREATED BY ULTRATHIN WEARABLE SENSORS WITH 100 SENSING PIXELS. CREDIT: POSTECH A pulse wave is a wave in which the blood flow – that originates from the heartbeat – is transmitted to the body. It is an important biosignal that indicates cardiovascular health. Analyzing...
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.) IMAGE: MARÍA GARCÍA GARCÍA, MIGUEL ÁNGEL DEL POZO BARRIUSO, LAURA SOTODOSOS-ALONSO, SARA SÁNCHEZ PERALES, JESÚS VÁZQUEZ, ENRIQUE CALVO, AND ASIER ECHARRI CREDIT: CNIC Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a nuclear import mechanism essential for organ growth and development. Manipulation of this mechanism has...
WOLTERS KLUWER HEALTH March 4, 2022 – Women who were younger at the time of their first menstrual period (menarche) are more likely to report chronic pain in adulthood, reports a study in PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published in the Lippincott portfolio by Wolters Kluwer. “[W]e found strong associations...
by University of Barcelona Effect of HFD and HFHFr on caloric intake, body weight, thermogenic markers in BAT, and inflammatory markers in liver: A) Bar plots showing the AUC of caloric intake for the full length of the study (3 months) corresponding to the three experimental groups studied: Control (CT), high fat diet (HFD), and...
by Tracy Cox, Pennsylvania State University Credit: Pixabay/CC0 Public Domain Nearly 11% of U.S. households experienced difficulty accessing food in 2020, according to the U.S. Department of Agriculture. With limited food options, food-insecure people tend to eat more red and processed meats. A study by Penn State College of Medicine researchers shows a link between...
by Sarah Small, Pennsylvania State University Qingguang Zhang, assistant research professor in engineering science and mechanics, is one of the Penn State researchers who developed a set of tools and methods for monitoring and analyzing brain activity, which they then published as a how-to guide Credit: Kelby Hochreither/Penn State Penn State researchers have developed a set...
To understand what causes Alzheimer’s disease and other forms of brain degeneration, scientists may need to look beyond the brain’s computational units, the neurons and synapses, and explore the vast infrastructure that supports them. Scientists have recognized for decades that the brains of people who die from advanced Alzheimer’s disease often exhibit severe damage to the...
