Month: <span>March 2022</span>

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Discovery may explain why more females than males get knee osteoarthritis
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Discovery may explain why more females than males get knee osteoarthritis

by Gillian Rutherford, University of Alberta Credit: Pixabay/CC0 Public Domain Female astronauts could avoid knee injuries during space flight—and better tests, prevention and treatments could be developed for knee osteoarthritis in women here on Earth—based on newly published research on the sex differences in knee meniscus tissue. Knee osteoarthritis is more common in females than...

Common cause of heart attacks in younger adults linked to gene variants
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Common cause of heart attacks in younger adults linked to gene variants

by Michael Morrison, Massachusetts General Hospital Credit: Pixabay/CC0 Public Domain Spontaneous coronary artery dissection (SCAD), a tear in an artery supplying blood to the heart, is a common cause of serious or fatal heart attacks that occur in women under age 50. Although the cause of SCAD is unknown, risk factors include female sex, recent childbirth, irregular...

Organoids reveal the tipping point when kidney damage turns irreversible
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Organoids reveal the tipping point when kidney damage turns irreversible

By Elizabeth Cooney March 2, 2022 Reprints Kidney organoids with markers of nephrons (purple, light blue, green) and stroma (red and yellow). Researchers used the miniature models to study when kidney damage turns irreversible.N. GUPTA, ET AL., SCIENCE TRANSLATIONAL MEDICINE Chronic kidney disease is a serious medical problem that changes the lives of about 13%...

MS: Keto diet may improve fatigue, mood, and quality of life
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MS: Keto diet may improve fatigue, mood, and quality of life

A recent study suggests that the keto diet might help some people with MS. martin-dm/Getty Images A preliminary study has found that participants with relapsing-remitting multiple sclerosis (MS) who followed a ketogenic diet for 6 months experienced improvements in fatigue, mood, and the quality of life. The study also demonstrated improvements in walking distance, disability,...

FDA approves cilta-cel for multiple myeloma
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FDA approves cilta-cel for multiple myeloma

A laboratory technician carries a cryogenic container of blood to be treated before genetically modifying a patient’s immune cells in the laboratory. March 8, 2019, at a production laboratory unit of the Paoli-Calmettes Institute in France. GERARD JULIEN/AFP via Getty Images On February 28, 2022, the Food and Drug Administration (FDA) approved ciltacabtagene autoleucel (cilta-cel)...

Had Omicron? You’re unlikely to catch its rising variant
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Had Omicron? You’re unlikely to catch its rising variant

Saima May Sidik A man is swabbed for SARS-CoV-2 in New Zealand, where the BA.2 subvariant on the rise. Credit: Adam Bradley/SOPA Images/LightRocket/Getty Good news for the pandemic-weary: a study1 shows that previous infection with the widely circulating BA.1 version of the Omicron coronavirus variant provides strong protection against its relative BA.2, which is growing in...

Will Omicron BA.2 become the next dominant variant?
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Will Omicron BA.2 become the next dominant variant?

By Dr. Priyom Bose, Ph.D. Feb 27 2022 Reviewed by Benedette Cuffari, M.Sc. The rapid outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has resulted in the coronavirus disease 2019 (COVID-19) pandemic. Since its emergence in 2019, SARS-CoV-2 has evolved due to multiple genomic mutations. The newly emerged SARS-CoV-2 variants have been classified as...

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DISCOVERY COULD LEAD TO TREATMENTS FOR TUMMY WOES IN KIDS WITH AUTISM

The findings could one day lead to individualized treatments aimed at easing their pain. David Beversdorf, a clinician at the University of Missouri Thompson Center for Autism and Neurodevelopmental Disorders, helps patients with autism spectrum disorder (ASD), many of whom may also be struggling with gastrointestinal or digestive issues, including constipation and diarrhea. Children with ASD...

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AI-designed protein awakens silenced genes, one by one

Technique allows researchers to toggle on individual genes that regulate cell growth, development and function. By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical “off switches” that silence them. Researchers from the University of Washington School of Medicine in Seattle describe...

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Surprisingly simple way mammals keep their bloodstream in balance

Chemists tend to think of the human body as operating out of a sense-and-respond paradigm. For example, you eat sugar, the pancreas senses the intake, and it responds by releasing the hormone insulin to keep your glucose levels in check. Scientists have long wondered whether there is a similar regulatory strategy for clearing other metabolites, like amino...