By Nick Lavars; March 27, 2022 Artist’s impression of mitochondrial transplantation using a specially developed syringe. IC: Sean Kilian Mitochondria are known as the powerhouses of the cells, taking in glucose and oxygen and producing energy in return. But this central role in cellular function means when things go awry it can have serious consequences...
Verifying the cause of allergic disorders
POHANG UNIVERSITY OF SCIENCE & TECHNOLOGY (POSTECH) Allergies are one of the most common health conditions in the world that affect 10 to 20% of Koreans. Although the disorder is accompanied by mild symptoms, it can lead to anaphylaxis, which is a severe and potentially life-threatening hypersensitivity to an environmental antigen. A leading cause of...
Dihydroartemisinin regulates splenic immune cell heterogeneity through SOD3-JNK-AP-1 Axis
SCIENCE CHINA PRESS IMAGE: DHA PROMOTED THE REVERSIBLE EXPANSION OF EFFECTIVE REGULATORY T CELLS (GREEN), INTERFERON-Γ+ CYTOTOXIC CD8+ T CELLS (RED), AND MHCIILOW FOLLICULAR (FO) B CELLS(BLUE) IN MOUSE SPLEEN (LEFT PANEL) VIA INDUCTION OF SUPEROXIDE DISMUTASE 3 (SOD3) EXPRESSION, INCREASED PHOSPHORYLATION OF C-JUN N-TERMINAL KINASES AND ITS DOWNSTREAM ACTIVATOR PROTEIN 1 TRANSCRIPTION FACTORS (RIGHT...
Scientists discover body’s natural alarm to battle blood loss
UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: UNIVERSITY OF VIRGINIA SCHOOL OF MEDICINE RESEARCHERS STEPHEN ABBOTT (FROM LEFT), DANIEL STORNETTA AND GEORGE SOUZA HAVE IDENTIFIED THE BODY’S NATURAL ALARM FOR BLOOD LOSS. CREDIT: COURTESY ABBOTT LAB University of Virginia School of Medicine scientists have discovered a cluster of cells in the brainstem that controls the body’s response...
Student-led study finds just 15% of CBD-infused oil, beverages, and other products are labeled correctly
by Katie Gerhards, University of Wisconsin-Madison Credit: Pixabay/CC0 Public Domain In 2018, the U.S. Food and Drug Administration approved the first prescription medication derived from cannabis sativa: Epidiolex. Used to treat seizures, Epidiolex is purified formulation of cannabidiol (CBD) and has been proven to significantly lower the frequency of seizures in some patients with devastating...
Head bump? here’s signs you need ER care
Knowing the signs of brain injury and when to seek emergency care could save a life, an expert says. “The brain is the body’s command center,” said Dr. Gillian Schmitz, president of the American College of Emergency Physicians. “One of the smartest ways to protect it is to be able to spot the signs of...
Stroke treatments safe and effective for people with existing disability or dementia
by American Heart Association Credit: CC0 Public Domain According to a new American Heart Association scientific statement, people with dementia or a pre-existing disability who receive timely and appropriate treatment for ischemic stroke (caused by a blood clot) may avoid additional disability and the subsequent health and financial impacts of stroke. The scientific statement, which...
Latest JAK inhibitor trials for severe skin disease are a success
by Jim Shelton, Yale University Before and after images for participants who received 36 weeks of treatment for alopecia areata with baricitinib. Credit: Yale University A new study shows that one in three patients with a severe skin disease were able to regrow hair after being treated with a common arthritis drug. The study is...
Disease severity linked to N protein of SARS-CoV-2
by King Abdullah University of Science and Technology From left: Sharif M. Hala, Sara Mfarrej, Professor Arnab Pain, Muhammad Shuaib and Tobias Mourier (not pictured) studied the N protein of SARS-CoV-2 to further understanding of its role in disease severity. Credit: King Abdullah University of Science and Technology A multicenter collaboration tracking the spread and...
Molecular key may unlock new treatments for neurodegenerative disorders
by Griffith University Structure of SARM1 in complex with inhibitor. Credit: Thomas Ve Researchers have worked out how to successfully switch off a key pathway of nerve fiber breakdown in debilitating neurodegenerative disorders such as Parkinson’s disease, traumatic brain injury and glaucoma. The study, led by Griffith University’s Institute for Glycomics and Disarm Therapeutics, a...