by Yale School of Public Health Credit: CC0 Public Domain A team of Yale-led researchers can now quantify the factors causing changes in the DNA that contribute most to cancer growth in tumors of most major tumor types. They write in a new paper, published in Molecular Biology and Evolution, that their new molecular analysis approach...
Study suggests obesity paradox for those over 80 due to non-cardiovascular disease mortality
by Bob Yirka, Medical Xpress Credit: Unsplash/CC0 Public Domain A team of researchers affiliated with multiple institutions in China and the U.S. has found that the obesity paradox for those over 80 is driven mostly by non-cardiovascular disease mortality rates. In their paper published in the journal Nature Aging, the group describes their study of...
Multicenter cohort study shows reduced risk of vision-threatening diabetic retinopathy from fenofibrate
by Bob Yirka, Medical Xpress Credit: Jenriquecf/Wikimedia Commons, CC BY-SA 4.0 A team of researchers at the University of Pennsylvania has found that administration of a drug currently used to reduce cholesterol levels in the bloodstream can reduce the risk of developing proliferative diabetic retinopathy (PDR) from non-proliferative diabetic retinopathy (NPDR). In their paper published in JAMA Ophthalmology, the...
Liver fibrosis: The fatal signaling pathway
by Medizinische Hochschule Hannover Professor Dr. Ingmar Mederacke. Credit: Medizinische Hochschule Hannover At least 5 million people in Germany suffer from liver disease. Fibrosis, the pathological proliferation of connective tissue, plays an important role in many complications of chronic liver problems. Activated hepatic stellate cells (HSCs) are massively involved in this tissue remodeling. An international...
Vaccine-derived polio is on the rise. A new vaccine aims to stop the spread
April 26, 2022 6:15 PM ET ARI DANIEL A health worker administers the oral polio vaccine to a young girl as other children wait for their turn at a school in Karachi, Pakistan on February 28, 2022. In response to an uptick in cases of vaccine-derived polio — a form of the disease that stems...
Fujifilm develops AI tech for predicting Alzheimer’s progression
By Adam Ang April 18, 2022 Detailed atrophy patterns that AI focused on predicting the progression to Alzheimer’s disease Credit: Fujifilm Corporation Fujifilm Corporation has developed AI technology that can predict whether patients with mild cognitive impairment will progress to Alzheimer’s disease within two years. According to a press statement, the AI Technology for AD...
Cellular regeneration therapy restores damaged liver tissue faster than ever
by Salk Institute Liver cells were partially reprogrammed into younger cells (red) using Yamanaka factors (white). The cell nuclei (blue) and cytoskeletal proteins (green) are also shown. Credit: Salk Institute Mammals can’t typically regenerate organs as efficiently as other vertebrates, such as fish and lizards. Now, Salk scientists have found a way to partially reset...
Scientists identify genetic variants linked to mobility changes in aging
by eLife A microscopic image of C. elegans roundworms used in a study to identify genetic variations that contribute to a build-up of oxidative stress, a process that can cause cell damage, in muscle tissue. Scientists screened the roundworms and found that variations in a gene called ALH-6 were associated with oxidative stress. Over time,...
Lipidomics provides new biomarkers for cardiovascular disease and Type 2 diabetes
DEUTSCHES ZENTRUM FUER DIABETESFORSCHUNG DZD IMAGE: LIPIDOMICS PROVIDES NEW BIOMARKERS FOR CARDIOVASCULAR DISEASE AND TYPE 2 DIABETES CREDIT: DIFE The lipid metabolism plays an important role in the development of cardiovascular diseases and type 2 diabetes. However, little is known about the molecular relationships. Using lipidomics, a modern analytical method, the team led by Dr....
Micronutrients (vitamins + minerals) show benefit for children with ADHD and emotional dysregulation
ELSEVIER Washington, DC, April 26, 2022 – A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, reports that children with ADHD and emotional regulation randomized to take a micronutrient formula were three times more likely to show symptomatic improvement on blinded clinician ratings, compared to those in the placebo group (54%...