NORTHWESTERN UNIVERSITY Daily prednisone promotes obesity, but weekly prednisone has ‘strikingly different’ results Weekly prednisone promotes nutrient uptake into muscles and improves lean body mass Many people take daily prednisone for immune conditions, resulting in weight gain and development of diabetes-like side effects CHICAGO — Obese mice that were fed a high-fat diet and that...
Month: <span>April 2022</span>
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Specialized liver blood vessel identity factor required for regeneration
by Weill Cornell Medical College Graphical abstract. Credit: Cell Stem Cell (2022). DOI: 10.1016/j.stem.2022.03.002 Researchers at Weill Cornell Medicine have identified a key protein that induces the program to build specialized liver blood vessels. The discovery could lead to engineered replacement hepatic tissue to treat common liver diseases. There are many types of blood vessels in the human...
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Mutations in noncoding DNA are found to protect the brain from ALS
by Weizmann Institute of Science Credit: CC0 Public Domain Genetic mutations linked to a disease often spell bad news. Mutations in over 25 genes, for example, are associated with amyotrophic lateral sclerosis, or ALS, and they all increase the risk of developing this incurable disorder. Now, a research team headed by Prof. Eran Hornstein of...
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First complete human genome poised to strengthen genetic analysis, study shows
by National Institute of Standards and Technology Credit: CC0 Public Domain Alongside the newly updated human genome, which fills in long-standing gaps to fully spell out the more than 3 billion letters that compose our genetic code, a separate companion study has shown it can serve as an accurate template that improves our DNA sequencing...
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Pandemic took a toll on teen mental health, US study says
by Mike Stobbe A student walks down a hallway between classes at a high school in Kansas City, Kan., on the first day of in-person learning Wednesday, March 30, 2021. According to a study by the Centers for Disease Control and Prevention released on Thursday, March 31, 2022, nearly half of U.S. high school students...
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Study sheds light on why immunodeficiency affects only one identical twin
by Wellcome Trust Sanger Institute Credit: CC0 Public Domain Scientists have long queried the causes of immune disorders in only one of two identical twins with identical genes. New research from the Wellcome Sanger Institute, the Josep Carreras Leukemia Research Institute in Spain and their collaborators, has found the answer lies in both alterations in...
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Vibrating Wearable Device May Help Nighttime GERD
Marcia Frellick March 30, 2022 A vibrating wearable device helped people with gastroesophageal reflux disease (GERD) stay positioned on their left side while sleeping, alleviating nighttime reflux symptoms compared with sham treatment, a small, randomized study suggests. People often report having more reflux symptoms when sleeping on their right side, and experimental studies suggest that...
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Study shows COVID-19’s lingering impacts on the brain
by Tulane University Tracy Fischer, PhD, lead investigator and associate professor of microbiology and immunology at the Tulane National Primate Research Center. Credit: Tulane University, Paula Burch-Celentano COVID-19 patients commonly report having headaches, confusion and other neurological symptoms, but doctors don’t fully understand how the disease targets the brain during infection. Now, researchers at Tulane...
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Here’s why you don’t need to feel sore after a workout to know it’s worked
by David R Clark, Carl Langan-Evans and Rob Erskine, The Conversation Delayed onset muscle soreness – better known as DOMS – is a common experience for many who exercise. Credit: Branislav Nenin/ Shutterstock “No pain, no gain” is a commonly used expression when it comes to getting in shape. It may also be why many of...
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Higher blood fats more harmful than first thought
by University of Leeds Microscopy image showing human muscle cells with nuclei in blue, and stress caused by the ceramide stress signals shown in red. Credit: Lee Roberts Increased levels of blood fats in people with type 2 diabetes and obesity are more harmful than previously thought, a new study has found. In patients with metabolic...