UNIVERSITÉ DE GENÈVE IMAGE: HYDRATION RESTORES THE AIRWAY SURFACE SEAL. IN TURQUOISE, THE JUNCTIONS BETWEEN THE EPITHELIAL CELLS (BLUE). CREDIT: UNIGE – LABORATORY OF PROF. MARC CHANSON Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure. It...
A potential new marker for personalized breast cancer therapy
by University of Southampton Inflammatory macrophages form on crown like structures surrounding breast tissue. Credit: University of Southampton A new study from the University of Southampton has discovered that “crown-like structures” surrounding breast tumors in overweight and obese patients could hinder their response to therapy. The findings of this study could potentially be used to improve...
Can medications for excessive alcohol use help prevent and treat alcohol-related liver disease?
by Massachusetts General Hospital Association of medical addiction therapy for alcohol use disorder with odds of hepatic decompensation within 10 years after cirrhosis diagnosis. Credit: JAMA Network Open (2022). DOI: 10.1001/jamanetworkopen.2022.13014 Excessive alcohol consumption can harm the liver, causing a range of conditions from relatively minor liver damage to serious problems such as cirrhosis and liver cancer—all...
Breakthrough COVID infections more likely in cancer and Alzheimer’s patients, studies find
by Case Western Reserve University Credit: Pixabay/CC0 Public Domain Breakthrough COVID-19 cases resulting in infections, hospitalizations and deaths are significantly more likely in cancer and Alzheimer’s patients, according to two new studies from researchers at the Case Western Reserve University School of Medicine. People within these diseases are often more susceptible to infection in general,...
Heart inflammation found in one in eight patients after hospitalization with COVID-19
by University of Glasgow Credit: Pixabay/CC0 Public Domain One in eight people who were hospitalized with COVID-19 between May 2020 and March 2021 were later diagnosed with myocarditis, or heart inflammation, according to major new research into the clinical long-term effects of COVID-19. The largest study of its kind to date was led by the...
A new statistical method for improved brain mapping
by Institut du Cerveau (Paris Brain Institute) Credit: Pixabay/CC0 Public Domain Brain mapping involves finding the brain regions associated with different traits, such as diseases, cognitive functions, or behaviors, and is a major field of research in neuroscience. This approach is based on statistical models and is subject to numerous biases. To try to counter...
Genetic test can diagnose certain immune system disorders
by Elsevier Credit: Pixabay/CC0 Public Domain Primary immunodeficiency disorders (PID) can result in chronic and sometimes life-threatening infections. More than 450 PIDs have been described, but timely and accurate diagnoses remain a challenge. In a new study in The Journal of Molecular Diagnostics, investigators used next-generation sequencing technology to test a DNA panel of 130 different...
Haywire T cells attack protein in “bad” cholesterol
by La Jolla Institute for Immunology T cells may drive inflammation as dangerous plaques build up in the cardiovascular system. Image from La Jolla Institute for Immunology. Credit: La Jolla Institute for Immunology Preventing atherosclerosis, the underlying cause of heart disease, means scientists need to understand how immune cells drive inflammation in the arteries. The challenge is that the T cells involved...
COVID affected taste and ‘Paxlovid mouth’ sounds disgusting: What causes dysgeusia
by Sarah Hellewell, The Conversation Credit: Shutterstock Loss or alteration of taste (dysgeusia) is a common symptom of COVID. It’s also a side effect of several illnesses and medications, including Paxlovid, the new antiviral medication to treat COVID infection. Although it affects fewer than 6% of people who are given Paxlovid, some report a “horrible” taste that came...
A subtle genetic change gives new clues about epilepsy
LINKÖPING UNIVERSITY IMAGE: ANTONIOS PANTAZIS, ASSOCIATE PROFESSOR AT THE DEPARTMENT OF BIOMEDICAL AND CLINICAL SCIENCES, AND THE WALLENBERG CENTER FOR MOLECULAR MEDICINE AT LINKÖPING UNIVERSITY. CREDIT: MAGNUS JOHANSSON/LINKÖPING UNIVERSITY Sometimes, even the alteration of a single nucleotide in a gene can cause serious disease. In a young boy with epilepsy, this kind of mutation has...