UNIVERSITY OF BRITISH COLUMBIA For the first time, researchers have shown what happens to the brain when a person receives a depression treatment known as repetitive transcranial magnetic stimulation (rTMS). The results were published today in the American Journal of Psychiatry. rTMS is a depression treatment typically used when other approaches — such as medications — haven’t...
Month: <span>May 2022</span>
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Dopamine makes you feel happy. But we probably have to be rewrite the textbooks
UNIVERSITY OF COPENHAGEN – THE FACULTY OF HEALTH AND MEDICAL SCIENCES “The textbooks probably have to be rewritten now.” Professor Claus Juul Løland from the Department of Neuroscience at the University of Copenhagen feels quite certain. A team of researchers headed by Claus Juul Løland has just published a study in the esteemed journal Nature Communications. The...
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Health screening, genetic tests might identify people at risk of premature heart disease
AMERICAN HEART ASSOCIATION DALLAS, May 18, 2022 — Health screening and genetic tests might identify more than 1 million U.S. adults who carry a gene for familial hypercholesterolemia, a common genetic disorder that causes elevated low-density lipoprotein (LDL) cholesterol, known as “bad cholesterol,” which may lead to premature heart attack or death, according to new research published today in...
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Healthy diet helps obese people with chronic inflammation and skin wound healing
UNIVERSITÄT LEIPZIG Image: Anja Saalbach Credit: Photo: Leipzig University In everyday clinical practice, it has been observed that chronic inflammatory diseases like psoriasis occur earlier and more severely in overweight people. In addition, they are more difficult to treat in patients with obesity. Experts at Leipzig University Hospital therefore wanted to find out why chronic...
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Researchers discover effective combination immunotherapy for liver cancer
UNIVERSITY OF MISSOURI-COLUMBIA IMAGE: CO-PRINCIPAL INVESTIGATOR GUANGFU LI, PHD, DVM, ASSOCIATE PROFESSOR IN THE DEPARTMENT OF SURGERY AND DEPARTMENT OF MOLECULAR MICROBIOLOGY AND IMMUNOLOGY AT THE UNIVERSITY OF MISSOURI SCHOOL OF MEDICINE. CREDIT: JUSTIN KELLEY/UNIVERSITY OF MISSOURI HEALTH CARE Researchers from the University of Missouri School of Medicine have discovered a specific combination immunotherapy that shows promise...
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Protein linked to intellectual disability has complex role
by Washington University School of Medicine Researchers at Washington University School of Medicine in St. Louis have identified a previously unknown function for the fragile X protein, the loss of which is the leading inherited cause of intellectual disability. The researchers showed that the protein modulates how neurons in the brain’s memory center process information,...
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Study reveals that kidney cells don’t filter blood, they pump it
by Gina Wadas, Johns Hopkins University Validation of ΔP in epithelial domes and theoretical pump performance curves. a Schematic of micro-needle inserted into a fluid filled epithelial dome. Asterisk indicates lumen side in the dome schematic (b). c Dashed rectangle shows phase-contrast image of oil-media interface in the micro-needle. The curvature of the interface was...
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mRNA vaccines like Pfizer and Moderna fare better against COVID-19 variants of concern
by Public Library of Science Credit: Unsplash/CC0 Public Domain A comparison of four COVID-19 vaccinations shows that messenger RNA (mRNA) vaccines from Pfizer-BioNTech and Moderna perform better against the World Health Organization’s variants of concern (VOCs) than viral vector vaccines from AstraZeneca and J&J/Janssen. Although they all effectively prevent severe disease by VOCs, the research,...
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Experimental ALS drug may be more effective than existing ones
by Northwestern University When mixed cortical cultures are established at P3, UMNs are labeled by eGFP expression in UCHL1-eGFP reporter mice, and express disease-causing proteins in reporter lines of mouse models of amyotrophic lateral sclerosis (ALS) (a-c) Generation of hSOD1G93A-UeGFP and WT-UeGFP littermate control mice. (d-e) UMNs in layer 5 of the primary motor cortex...
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Type-I interferon stops immune system from ‘going rogue’ during viral infections
by McMaster University Credit: CC0 Public Domain McMaster University researchers have found not only how some viral infections cause severe tissue damage, but also how to reduce that damage. They have discovered how Type I interferon (IFN) stops the immune system from “going rogue” and attacking the body’s own tissues when fighting viral infections, including COVID-19....