By Mark Waghorn via SWNS Milk may hold the key to beating brain cancer, according to new research. It can deliver gene silencing drugs that shrink deadly tumors. The white stuff contains chemicals that can carry siRNA’s (small interfering RNAs) that prevent manufacture of proteins that fuel the growths. Currently, the dairy food’s nanoparticles are being cultured...
Month: <span>May 2022</span>
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Study finds that psychopaths remain just as bad, or worse, as they age
by University of Otago Credit: Pixabay/CC0 Public Domain Anyone waiting for a sociopath to grow up or calm down should give up; they will not change, a new study has revealed. The research, published in the International Journal of Offender Therapy and Comparative Criminology, surveyed more than 1,200 partners, family members and friends of psychopaths—93% reported they were...
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Nanobiotics: Model predicts how nanoparticles interact with proteins
Nanoengineered drugs that stop harmful bacteria and viruses could be on the horizon. With antibiotic-resistant infections on the rise and a continually morphing pandemic virus, it’s easy to see why researchers want to be able to design engineered nanoparticles that can shut down these infections. A new machine learning model that predicts interactions between nanoparticles...
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Gene-editing improved with chemical process
Case Western Reserve University researchers combine novel chemical method with CRISPR gene-editing tools to target disease-specific versions of genetic code. The gene-editing technique known as CRISPR accelerated biological and medical research in the last decade by allowing scientists to repair the DNA of human cells almost as simple as using a pair of scissors. Gene-editing—and especially CRISPR,...
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A new biomarker for blood–brain barrier dysfunction in Alzheimer’s disease
NAGOYA CITY UNIVERSITY IMAGE: BBB KW MAP (A), QSM (B), AND [11C]PIB-PET SUVR (C) FROM AN APOE Ɛ4 NONCARRIER (Ε3/Ε3), A HETEROZYGOTE (Ε3/Ε4), AND A HOMOZYGOTE (Ε4/Ε4) ARE DISPLAYED. CREDIT: NAGOYA CITY UNVIERSITY Alzheimer’s disease (AD) is the most common type of dementia. An etiology of AD would be excessive accumulation of toxic forms of...
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High-fat diet linked to nitric oxide levels, cancer development
BECKMAN INSTITUTE FOR ADVANCED SCIENCE AND TECHNOLOGY IMAGE: JEFFERSON CHAN (LEFT), AN ASSOCIATE PROFESSOR OF CHEMISTRY AT THE UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN, AND ANUJ YADAV (RIGHT), A SENIOR RESEARCH ASSOCIATE, WERE PART OF A TEAM THAT DEMONSTRATED A DIRECT LINK BETWEEN A HIGH-FAT DIET AND HEIGHTENED NITRIC OXIDE LEVELS, WHICH CAN LEAD TO INCREASED RISK...
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Big study answers treatment question for little known kidney condition
GEORGE INSTITUTE FOR GLOBAL HEALTH The largest ever randomized controlled trial in IgA nephropathy has found that treatment with methylprednisolone – a cheap, widely used corticosteroid drug – halves the risk of losing kidney function and kidney failure, and that this can be effectively achieved with fewer side effects if a reduced dose is used....
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Clinical study shows postbiotic urolithin a improves muscle strength and exercise performance in middle aged adults
ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE Age-associated muscle decline can start as early as 40 years old and there are currently no effective interventions to counteract it other than exercise. A new milestone study published today in Cell Reports Medicine showed that daily intake of Amazentis’ proprietary Urolithin A, Mitopure, significantly improved muscle strength by 12% after four months....
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Binge drinking has a powerful impact on the adolescent brain
by Ellen Goldbaum, University at Buffalo Credit: Pixabay/CC0 Public Domain Binge drinking is the most common, costly and deadly pattern of excessive alcohol use in the U.S., according to the U.S. Centers for Disease Control and Prevention. Defined as consuming five or more drinks in a 2-hour period for men or four or more drinks...
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Drug combination reduces the risk of asthma attacks
by Rutgers University Credit: CC0 Public Domain A global study of asthma patients by Rutgers and an international team of researchers found a combination of two drugs dramatically reduces the chances of suffering an asthma attack. Results from the clinical trial called MANDALA, published in The New England Journal of Medicine, show that a combination of...