by University of South Australia Credit: Pixabay/CC0 Public Domain South Australian scientists have made a significant breakthrough in overcoming drug resistance in acute myeloid leukemia (AML), a rare and devastating blood cancer that kills most patients within a few years. In a new study published in the hematology journal Blood, researchers from UniSA and SA Pathology’s...
Methylation of tRNA-derived fragments regulates gene-silencing activity in bladder cancer
by By Jeff Hansen, University of Alabama at Birmingham Systematic mapping of m1A sites in small RNA space. a) Chemical structure of m1A (N1-methyladenosine). b) Overall m1A mapping strategy for small RNAs by combining m1A RIP and m1A-induced mismatch analysis. Synthetic m1A RNA is included as a positive control. c) TGIRT identified as the optimal...
The Most Horrible Parasite: Brain Eating Amoeba
This post is not for the faint-hearted. However, parasites are a real thing, and it is helpful to know what sometimes doctors need to deal with. This time we’ll talk about amoebas. There is a large diversity of these single-celled organisms in the world, and absolute majority of them are harmless to humans, especially when our immune system is...
Study: Early Warning System for Alzheimer’s Disease?
The accumulation of amyloid-beta and tau proteins in the brain is linked to Alzheimer’s disease, and now research shows that such accumulation can disrupt connections between brain structures important for memory. The new study, led by investigators at Harvard Medical School and Massachusetts General Hospital and published in PNAS, revealed that these disrupted connections were present years before...
A better diet helps beat depression in young men
UNIVERSITY OF TECHNOLOGY SYDNEY IMAGE: COLOURFUL VEGETABLES CREDIT: NO ATTRIBUTION REQUIRED Young men with a poor diet saw a significant improvement in their symptoms of depression when they switched to a healthy Mediterranean diet, a new study shows. Depression is a common mental health condition that affects approximately 1 million Australians each year. It is...
Study sheds light on treatment of hyperkalaemia
STELLENBOSCH UNIVERSITY Medical specialists urgently need more knowledge on how to treat and manage hyperkalaemia (too much potassium in the blood), which may cause respiratory muscle weakness and potentially fatal heart rhythm disturbance. This is according to a new study at Stellenbosch University (SU) in South Africa. “We found that there is a paucity of...
New therapy shown to be effective in women with fibromyalgia and depression
UNIVERSITAT OBERTA DE CATALUNYA (UOC) IMAGE: PERSONAL CONSTRUCT THERAPY IMPROVES SYMPTOMS OF DEPRESSION IN WOMEN WITH FIBROMYALGIA CREDIT: CHRONIC JOY MINISTRY Fibromyalgia is a rheumatic disease of unknown origin, which is characterized by chronic pain and often accompanied by symptoms of depression. It mainly affects women, and there is no cure, but various treatments can help relieve...
More coronary disease among COPD patients
THE UNIVERSITY OF BERGEN IMAGE: CHRISTINA DUE SVENDSEN CREDIT: PRIVATE Previous registry studies have given reason to suspect COPD patients more often have coronary disease than what can be expected from smoking habits, gender, and age. However, there has been a lack of studies with more invasive measurements of coronary disease among COPD patients. Patients...
Target to make immunotherapy for cancer safer, while more effective
OCHSNER HEALTH SYSTEM IMAGE: DANIEL JOHNSON, MD, IS A LEAD AUTHOR ON A CANCER CELL STUDY SHOWING THAT BLOCKING THE EXPRESSION OF IL-6 COULD DE-COUPLE AUTOIMMUNITY FROM ANTITUMOR IMMUNITY. CREDIT: OCHSNER HEALTH Immune checkpoint inhibitors have revolutionized the treatment of many cancers by using our body’s immune system to kill cancer. These treatments sometimes can...
Stem cells could help prevent diabetes onset from cancer immunotherapy
By Michael Irving May 08, 2022 Mesenchymal stem cells have shown promise in tests in mice for preventing type 1 diabetes developing as a side effect of cancer immunotherapy Depositphotos Type 1 diabetes can be a rare but serious side effect of a cancer treatment that use what are known as immune checkpoint inhibitors. In...