Dextromethorphan, or DXM, is a cough suppressant that is an ingredient in over-the-counter (OTC) cold medications. When people take DXM in high doses, it can cause hallucinations and feelings of euphoria. However, overdosing on DXM can be dangerous. When people take the correct dosage of a cough medication, DXM does not pose a risk. However,...
Long-COVID Symptoms a Serious Challenge for Older Patients, Physicians
Bridget M. Kuehn April 27, 2022 Even mundane tasks like making a meal can be exhausting for Louise Salant. “I’m totally wiped out,” said the 71-year-old former private music instructor with asthma who lives in New York City and has been coping with debilitating symptoms of fatigue, shortness of breath, and gastrointestinal symptoms since recovering from a...
Why Are We Still Prescribing Angiotensin-Converting Enzyme Inhibitors?
Franz H. Messerli, MD; Chirag Bavishi, MD, MPH; Sripal Bangalore, MD, MHA Abstract and Introduction Introduction The human understanding when it has once adopted an opinion (either as being the received opinion or as being agreeable to itself) draws all things else to support and agree with it.—Sir Francis Bacon, 1620 Prospective randomized controlled trials...
‘Eye-catching’ smartphone app could make it easy to screen for neurological disease at home
UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: A SMARTPHONE USER CAN IMAGE THE EYE USING THE RGB SELFIE CAMERA AND THE FRONT-FACING NEAR-INFRARED CAMERA INCLUDED FOR FACIAL RECOGNITION. MEASUREMENTS FROM THIS IMAGING COULD BE USED TO ASSESS THE USER’S COGNITIVE CONDITION. CREDIT: DIGITAL HEALTH LAB Researchers at the University of California San Diego have developed...
Insulin spray improved gait, cognitive function in patients with and without type 2 diabetes, clinical trial shows
BETH ISRAEL DEACONESS MEDICAL CENTER BOSTON – An estimated 25 percent of people older than 65 have type 2 diabetes, a condition in which the body cannot produce enough insulin to effectively manage blood sugar. Insulin plays an important role in the brain, and people with prediabetes and diabetes are at increased risk of Alzheimer’s disease...
A new mutation behind synucleinopathies
ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE Parkinson’s disease and Lewy body dementia belong to a family of neurodegenerative disorders called synucleinopathies because they are caused by the pathological accumulation of protein alpha-synuclein into structures called Lewy bodies and Lewy neurites in the brain. In a healthy brain, alpha-synuclein is found in synapses as distinct proteins called...
Explaining how Ritalin sharpens attention
by Patrick Monahan, University of Pittsburgh Credit: CC0 Public Domain Even half a century after a drug comes on the market, scientists can still learn new things about how it works. New research from University of Pittsburgh neuroscientists provides a rare look at how Ritalin affects activity in the brains of animals, providing a deeper...
Review: Transcranial direct current stimulation eases migraine
Credit: Pixabay/CC0 Public Domain Transcranial direct current stimulation (tDCS) is effective and safe for migraine, according to a review published online April 19 in CNS Neuroscience and Therapeutics. Peiwei Hong, from Sichuan University in Chengdu, China, and colleagues conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to examine the efficacy and safety of tDCS for migraine. The...
Osteoporosis in men overlooked by doctors and patients
by University of Sheffield Credit: Pixabay/CC0 Public Domain Osteoporosis in men is often overlooked by health care professionals, a study in The Lancet Diabetes and Endocrinology from the University of Sheffield has found. Researchers say raising awareness of the condition in men is desperately needed to help improve outcomes for patients. Osteoporosis is a condition where the...
A novel therapy ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet
by University of Alabama at Birmingham Credit: Unsplash/CC0 Public Domain A novel therapy developed at the University of Alabama at Birmingham ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet. The therapy acts through sustained release of nitric oxide, a gaseous signaling chemical whose most important function in the body is relaxing...